Measuring a level of a 5-hydroxymethylcytosine in a sample from a subject having a cancer or suspected of having cancer

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 10,041,938, 2018 - Google Patents
US10041938B2 - Measuring a level of a 5-hydroxymethylcytosine in a sample from a subject
having a cancer or suspected of having cancer - Google Patents US10041938B2 - Measuring …

Selective oxidation of 5-methylcytosine by TET-family proteins

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 10,031,131, 2018 - Google Patents
US10031131B2 - Selective oxidation of 5-methylcytosine by TET-family proteins - Google
Patents US10031131B2 - Selective oxidation of 5-methylcytosine by TET-family proteins …

Detection of 5-hydroxymethylcytosine by glycosylation

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 9,816,986, 2017 - Google Patents
US9816986B2 - Detection of 5-hydroxymethylcytosine by glycosylation - Google Patents
US9816986B2 - Detection of 5-hydroxymethylcytosine by glycosylation - Google Patents …

Methods for detection of nucleotide modification

MJ Booth, S Balasubramanian - US Patent 10,428,381, 2019 - Google Patents
This invention relates to the identification of modified cytosine residues, such as 5-
methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) to be …

Selective oxidation of 5-methylcytosine by TET-family proteins

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 10,533,213, 2020 - Google Patents
US10533213B2 - Selective oxidation of 5-methylcytosine by TET-family proteins - Google
Patents US10533213B2 - Selective oxidation of 5-methylcytosine by TET-family proteins …

Selective oxidation of 5-methylcytosine by TET-family proteins

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 10,731,204, 2020 - Google Patents
2018-03-23 Assigned to IMMUNE DISEASE INSTITUTE, INC. reassignment IMMUNE
DISEASE INSTITUTE, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Selective oxidation of 5-methylcytosine by TET-family proteins

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 10,323,269, 2019 - Google Patents
The present invention provides for novel methods for regulating and detecting the cytosine
methylation status of DNA. The invention is based upon identification of a novel and …

Oxidizing agent for modified nucleotides

T Ost - US Patent 10,563,248, 2020 - Google Patents
This invention relates to the use of metal (VI) oxo com plexes to catalyse the selective
oxidation of 5hmC residues in polynucleotides to 5fC residues. This may be useful in the …

Selective oxidation of 5-methylcytosine by TET-family proteins

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 10,612,076, 2020 - Google Patents
US10612076B2 - Selective oxidation of 5-methylcytosine by TET-family proteins - Google
Patents US10612076B2 - Selective oxidation of 5-methylcytosine by TET-family proteins …

Selective oxidation of 5-methylcytosine by TET-family proteins

A Rao, M Tahiliani, KP Koh, S Agarwal… - US Patent 10,443,091, 2019 - Google Patents
The present invention provides for novel methods for regulating and detecting the cytosine
methylation status of DNA. The invention is based upon identification of a novel and …