Chondrogenesis occurs as a result of mesenchymal cell condensation and
chondroprogenitor cell differentiation. Following chondrogenesis, the chondrocytes remain …

Osteoarthritis (OA) is an extremely prevalent age-related condition. The economic and
societal burden due to the cost of symptomatic treatment, inability to work, joint replacement …

Human cartilage is a complex tissue of matrix proteins that vary in amount and orientation
from superficial to deep layers and from loaded to unloaded zones. A major challenge to …

Osteoarthritis (OA) is a common degenerative condition that afflicts more than 70% of the
population between 55 and 77 years of age. Although its prevalence is rising globally with …

Stem cells are promising candidate cells for regenerative applications because they
possess high proliferative capacity and the potential to differentiate into other cell types …

Aging is the most prominent risk factor triggering several degenerative diseases, such as
osteoarthritis (OA). Due to its poor self-healing capacity, once injured cartilage needs to be …

Oxidative stress (OS) contributes to Osteoarthritis (OA) pathogenesis and its effects are
worsened by the impairment of homeostatic mechanisms such as autophagy in OA …

Osteoarthritis is the most common arthritic condition, which involves progressive
degeneration of articular cartilage. The most recent accomplishments have significantly …

Osteoarthritis (OA) is a degenerative joint disease affecting a large population of people.
Although the elevated expression of PKR (double stranded RNA-dependent protein kinase) …

Multiple myeloma (MM) cells secrete osteoclastogenic factors that promote osteolytic
lesions; however, the identity of these factors is largely unknown. Here, we performed a …