Biochemical changes to the inner ear contributing to diabetes-induced hearing loss: possible pharmacological targets for therapy
A Gedawy, H Al-Salami, CR Dass - Journal of Pharmacy and …, 2024 - academic.oup.com
Objectives Biochemical alterations due to diabetes development and progress are complex
and diabetes-associated injury to various tissues has been well reported. Nevertheless, a …
and diabetes-associated injury to various tissues has been well reported. Nevertheless, a …
Analysis of drug-induced hearing loss by using a spontaneous reporting system database
M Tanaka, S Hasegawa, S Nakao, K Shimada… - PLoS …, 2019 - journals.plos.org
Many drugs can cause hearing loss, leading to sensorineural deafness. The aim of this
study was to evaluate the risk of drug-induced hearing loss (DIHL) by using the Japanese …
study was to evaluate the risk of drug-induced hearing loss (DIHL) by using the Japanese …
Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin
L Yao, J Zhang, B Chen, M Cai, D Feng… - Acta Pharmacologica …, 2020 - nature.com
Abstract Etimicin (ETM), a fourth-generation aminoglycosides (AGs), is now widely clinically
used in China due to its high efficacy and low toxicity. However, the mechanisms underlying …
used in China due to its high efficacy and low toxicity. However, the mechanisms underlying …
Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene
M Palomar-Siles, V Yurevych, VJN Bykov, KG Wiman - Plos one, 2023 - journals.plos.org
The retinoblastoma protein (Rb) is encoded by the RB1 tumor suppressor gene. Inactivation
of RB1 by inherited or somatic mutation occurs in retinoblastoma and various other types of …
of RB1 by inherited or somatic mutation occurs in retinoblastoma and various other types of …
Therapeutic potential of salidroside in preserving rat cochlea organ of corti from gentamicin-induced injury through modulation of NRF2 signaling and GSK3β/NF-κB …
Y Zhang, S Yu, X Guo, L Wang, L Yu, P Wang - Plos one, 2024 - journals.plos.org
Salidroside (SAL) is a phenol glycoside compound found in plants of the Rhodiola genus
which has natural antioxidant and free radical scavenging properties. SAL are able to …
which has natural antioxidant and free radical scavenging properties. SAL are able to …
Aminoglycosides—alive and well in treatment of pediatric infections: a case of benefit versus risk
N Le Saux, J Robinson - Official Journal of the Association …, 2018 - jammi.utpjournals.press
Aminoglycosides (in the form of streptomycin) were first isolated from Streptomyces griseus
in 1944 and were considered a breakthrough in therapy, especially for tuberculosis. Since …
in 1944 and were considered a breakthrough in therapy, especially for tuberculosis. Since …
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O Italica - 2010 - iris.unict.it
La rivista pubblica in inglese lavori originali di interesse otorinolaringologico, gli atti ufficiali
della Società, editoriali, note di attualità, recensioni, rubriche redazionali, notizie sindacali. I …
della Società, editoriali, note di attualità, recensioni, rubriche redazionali, notizie sindacali. I …