Within the natural products field there is an increasing emphasis on the study of compounds
from microbial sources. This has been fuelled by interest in the central role that …

The implementation of ortho-quinone methide (o-QM) intermediates in complex molecule
assembly represents a remarkably efficient strategy designed by Nature and utilized by …

Natural sesquiterpenoids caryophyllene and caryophyllene oxide are important resources
for organic and medicinal chemistry. Due to their peculiar structure, these sesquiterpenoids …

Natural products perennially serve as prolific sources of drug leads and chemical probes,
fueling the development of numerous therapeutics. Despite their scarcity, natural products …

Rhodomentosones A and B (1 and 2), two pairs of novel enantiomeric phloroglucinol trimers
featuring a unique 6/5/5/6/5/5/6-fused ring system were isolated from Rhodomyrtus …

The first total synthesis of guajavadimer A, a dimeric caryophyllene-derived meroterpenoid
featuring an unprecedented 4–9–6–6–6–9–4-fused ring system, is reported. Key to the …

NMR fingerprints provide powerful tools to identify natural products in complex mixtures.
Principal component analysis and machine learning using 1H and 13C NMR data …

The convergent biomimetic gram-scale synthesis of disesquiterpenoid ester rumphellolide J
is described. 4β, 8β-Epoxycaryophyllan-5-ol was prepared in 67% yield (1.4 g) from …

Rhodotomentones A and B (1 and 2), two unusual caryophyllene-derived meroterpenoids
(CDMTs) featuring a rare 6/6/9/4/6/6 hexacyclic ring system, along with their biogenetically …

Cyclobutanes with a gem‐dimethyl group are common motifs in natural products. However,
strategies for constructing enantioenriched gem‐dimethyl cyclobutanes are still …