▪ Abstract The lung collectins, SP-A and SP-D, are important components of the innate
immune response to microbial challenge and participate in other aspects of immune and …

The possibility that the lipoprotein complex of lung surfactant functions in pulmonary host
defense as well as lowering surface tension at the air-liquid interface has been the subject of …

Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

The use of simulated biological fluids (SBFs) is a promising in vitro technique to better
understand the release mechanisms and possible in vivo behaviour of materials, including …

Lung surfactant protein-D (SP-D), a collectin mainly produced by alveolar type II cells,
initiates the effector mechanisms of innate immunity on binding to microbial carbohydrates …

Pulmonary alveolar proteinosis was first described by Rosen et al in 1958. 1 It is an unusual
diVuse lung disease characterised by the accumulation of large amounts of a …

We tested the hypothesis that pulmonary surfactant-associated lectins--surfactant proteins A
and D (SP-A, and-D)--contribute to initial protective mechanisms against influenza A viruses …

This article starts with a brief account of the history of research on pulmonary surfactant. We
will then discuss the morphological aspects and composition of the pulmonary surfactant …

Mice lacking surfactant protein (SP)-A (SP-A−/−) or SP-D (SP-D−/−) and wild-type mice were
infected with group B streptococcus or Haemophilus influenzae by intratracheal instillation …

The surfactant-associated proteins SP-A and SP-D are members of a family of collagenous
host defense lectins, designated collectins. There is increasing evidence that these …