From Low to No O2-Dependent Hypoxia Photodynamic Therapy (hPDT): A New Perspective
Conspectus The advent of photochemical techniques has revolutionized the landscape of
biology and medical sciences. Especially appealing in this context is photodynamic therapy …
biology and medical sciences. Especially appealing in this context is photodynamic therapy …
Photon-controlled pyroptosis activation (photopyro): an emerging trigger for antitumor immune response
Pyroptosis refers to the process of gasdermin-mediated lytic programmed cell death (PCD)
characterized by the release of pro-inflammatory cytokines. Our knowledge of pyroptosis has …
characterized by the release of pro-inflammatory cytokines. Our knowledge of pyroptosis has …
Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Nickel(II) Phototheranostics: A Case Study in Photoactivated H2O2-Enhanced Immunotherapy
R Zhang, H Xu, Y Yao, G Ran, W Zhang… - Journal of the …, 2023 - ACS Publications
Phototheranostics have emerged as a promising subset of cancer theranostics owing to their
potential to provide precise photoinduced diagnoses and therapeutic outcomes. However …
potential to provide precise photoinduced diagnoses and therapeutic outcomes. However …
Overcoming the Oxygen Dilemma in Photoredox Catalysis: Near‐Infrared (NIR) Light‐Triggered Peroxynitrite Generation for Antibacterial Applications
Z Shen, S Zheng, Y Fang, G Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
The peroxynitrite anion (ONOO−) is closely associated with many diseases and the creation
of ONOO− donors is an essential means of understanding its pathophysiological functions …
of ONOO− donors is an essential means of understanding its pathophysiological functions …
Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium (III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and …
J Kasparkova, A Hernández-García… - Journal of Medicinal …, 2023 - ACS Publications
A second-generation series of biscyclometalated 2-(5-aryl-thienyl)-benzimidazole and-
benzothiazole Ir (III) dppz complexes [Ir (C^ N) 2 (dppz)]+, Ir1–Ir4, were rationally designed …
benzothiazole Ir (III) dppz complexes [Ir (C^ N) 2 (dppz)]+, Ir1–Ir4, were rationally designed …
Photo-controllable biochemistry: Exploiting the photocages in phototherapeutic window
Photochemical tools have revolutionized the landscape of biomedicine, enabling the
exploration of nature in a noninvasively remote-controlled manner. Among them, especially …
exploration of nature in a noninvasively remote-controlled manner. Among them, especially …
Covalent organic framework nanoparticles: Overcoming the challenges of hypoxia in cancer therapy
Hypoxia, or low oxygen levels, is a common feature of the tumor microenvironment. It is
caused by the aggressive proliferation of cancer cells, which consume more oxygen than …
caused by the aggressive proliferation of cancer cells, which consume more oxygen than …
Copper-loaded nanoheterojunction enables superb orthotopic osteosarcoma therapy via oxidative stress and cell cuproptosis
J Xia, C Hu, Y Ji, M Wang, Y Jin, L Ye, D Xie, S Jiang… - ACS …, 2023 - ACS Publications
Catalytic tumor therapy based on two-dimensional (2D) nanomaterials is a burgeoning and
promising tumor therapeutic modality. However, the inefficient utilization and conversion of …
promising tumor therapeutic modality. However, the inefficient utilization and conversion of …
Enhanced photodynamic therapy by improved light energy capture efficiency of porphyrin photosensitizers
Z Tian, H Li, Z Liu, L Yang, C Zhang, J He, W Ai… - … Treatment Options in …, 2023 - Springer
Opinion Statement Photodynamic therapy (PDT) has garnered increasing attention in cancer
treatment because of its advantages such as minimal invasiveness and selective …
treatment because of its advantages such as minimal invasiveness and selective …