Acute disseminated encephalomyelitis (ADEM) is an immune-mediated demyelinating CNS
disorder with predilection to early childhood. ADEM is generally considered a monophasic …

Purpose of review This review presents a comprehensive analysis of the current high-
efficacy disease-modifying therapies (DMTs) available for treatment of multiple sclerosis …

The clinical features, diagnostic challenges, neuroimaging appearance, therapeutic options,
and pathobiological research progress in childhood—and adolescent—onset multiple …

New therapies are being evaluated by clinical trials and, if efficacious, introduced for the
treatment of adult MS. The role of these new and existing agents in the management of …

Corticosteroids are the mainstay of therapy for many pediatric disorders and sometimes are
life-saving. Both endogenous and synthetic derivatives diffuse across the cell membrane …

Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of
the central nervous system that typically presents in childhood and is associated with …

Acute disseminated encephalomyelitis is an immune-mediated inflammatory and
demyelinating disorder of the central nervous system, commonly preceded by an infection. It …

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated, inflammatory
demyelinating disease of the central nervous system (CNS) that usually affects children and …

Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory, demyelinating
disorder of the CNS. Only in the past 15 years have larger groups of patients from several …

To expand current knowledge, we examined the safety and tolerability of subcutaneous
interferon β-1a in patients with pediatric-onset multiple sclerosis. Records from 307 patients …