Platelets are small anucleated blood cells primarily known for their vital hemostatic role.
Allogeneic platelet concentrates (PCs) collected from healthy donors are an essential …

Platelet transfusions carry greater risks of infection, sepsis, and death than any other blood
product, owing primarily to bacterial contamination. Many patients may be at particular risk …

Purpose To provide evidence-based guidance on the use of platelet transfusion in people
with cancer. This guideline updates and replaces the previous ASCO platelet transfusion …

Background Platelet transfusions are used to prevent and treat bleeding in people who are
thrombocytopenic. Despite improvements in donor screening and laboratory testing, a small …

Introduction: Despite mitigation strategies that include the exclusion of females from plasma
donation or the exclusion of females with a history of pregnancy or known anti-leukocyte …

Transfusion-related acute lung injury (TRALI) is a severe adverse event and a leading cause
of transfusion-associated death. Its poor associated prognosis is due, in large part, to the …

BACKGROUND Delayed, large‐volume bacterial culture and amotosalen/ultraviolet‐A light
pathogen reduction are effective at reducing the risk of bacterial proliferation in platelet …

BACKGROUND The INTERCEPT Blood System pathogen reduction technology (PRT),
which uses amotosalen and ultraviolet A light treatment (amotosalen/UV‐PRT), inactivates …

Transfusion reactions are common occurrences, and clinicians who order or transfuse blood
components need to be able to recognize adverse sequelae of transfusion. The differential …

BACKGROUND Two noninferiority, randomized, controlled trials were conducted in parallel
comparing the safety and efficacy of platelets treated with Intercept or Mirasol pathogen …