Osteoarthritis (OA), characterized by joint malfunction and chronic disability, is the most
common form of arthritis. Clinical and animal experiments reveal that age-related OA is …

Inflammation is a variable feature of osteoarthritis (OA), associated with joint symptoms and
progression of disease. Signs of inflammation can be observed in joint fluids and tissues …

Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

Background Bariatric (weight loss) surgery for obesity is considered when other treatments
have failed. The effects of the available bariatric procedures compared with medical …

This paper provides an up-to-date review of obesity and lower limb osteoarthritis (OA). OA is
a major global cause of disability, with the knee being the most frequently affected joint …

Osteoarthritis (OA) is the most prevalent chronic rheumatic diseases worldwide, with a
strong impact on individual and population health. OA is a clinically heterogeneous disease …

The objective of this article is to deliver a concise up-to-date review on hip osteoarthritis. We
describe the epidemiology (disease distribution), etiologies (associated risk factors) …

OA is a degenerative joint disease characterized by articular cartilage degradation,
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …

OBJECTIVE: Knee osteoarthritis (OA) is common in older adults. Determination of risk
factors for onset of knee OA may help in its prevention. The objective of this systematic …

Biomechanical factors play an important role in the health of diarthrodial joints. Altered joint
loading–associated to obesity, malalignment, trauma or joint instability–is a critical risk factor …