The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …

Innate and adaptive immune cell activation and infiltration is the key characteristic of tissue
inflammation. The innate immune system is the front line of host defense in which innate …

Inflammatory cytokines are highly inducible small glycoproteins or regulatory proteins of low
molecular weight secreted by different cell types. They regulate intercellular communication …

Biophysical cues of rigid tumor matrix play a critical role in cancer cell malignancy. We report
that stiffly confined cancer cells exhibit robust growth of spheroids in the stiff hydrogel that …

Inflammation, Atherosclerosis, and Coronary Artery Disease | New England Journal of Medicine
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Atherosclerosis, the cause of myocardial infarction, stroke, and ischemic gangrene, is an
inflammatory disease. The atherosclerotic process is initiated when cholesterol-containing …

Various stress factors leading to protein damage induce the activation of an evolutionarily
conserved cell protective mechanism, the heat shock response (HSR), to maintain protein …

Extensive work has suggested that a number of endogenous molecules such as heat shock
proteins (hsp) may be potent activators of the innate immune system capable of inducing …

Recent epidemiologic studies have shown that aerobic exercise, one of lifestyle
modifications, reduces cardiovascular morbidity and mortality in the general population …

The tumor cell signaling pathways that trigger the uncontrolled proliferation, resistance to
apoptosis, metastasis and escape from immune surveillance are partially understood. Toll …