Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

We created nanometer-scale transmembrane channels in lipid bilayers by means of self-
assembled DNA-based nanostructures. Scaffolded DNA origami was used to create a stem …

The electrical current blockade of a peptide or protein threading through a nanopore can be
used as a fingerprint of the molecule in biosensor applications. However, threading of full …

Proteins are structurally dynamic macromolecules, and it is challenging to quantify the
conformational properties of their native state in solution. Nanopores can be efficient tools to …

A nanopore-based device provides single-molecule detection and analytical capabilities
that are achieved by electrophoretically driving molecules in solution through a nano-scale …

Nanotechnology is a multidisciplinary field, which covers a vast and diverse array of devices
derived from engineering, biology, physics and chemistry. These devices include …

We report on DNA translocations through nanopores created in graphene membranes.
Devices consist of 1− 5 nm thick graphene membranes with electron-beam sculpted …

Provided herein are methods and devices for characterizing a biomolecule parameter by a
nanopore-containing mem brane, and also methods for making devices that can be used in …

Sensitivity and specificity are two most important factors to take into account for molecule
sensing, chemical detection and disease diagnosis. A perfect sensitivity is to reach the level …