A consensus on criteria for cure of acromegaly
A Giustina, P Chanson, MD Bronstein… - The Journal of …, 2010 - academic.oup.com
Objective: The Acromegaly Consensus Group met in April 2009 to revisit the guidelines on
criteria for cure as defined in 2000. Participants: Participants included 74 neurosurgeons …
criteria for cure as defined in 2000. Participants: Participants included 74 neurosurgeons …
Acromegaly pathogenesis and treatment
S Melmed - The Journal of clinical investigation, 2009 - Am Soc Clin Investig
Dysregulated growth hormone (GH) hypersecretion is usually caused by a GH-secreting
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …
Criteria for cure of acromegaly: a consensus statement
In February 1999, a workshop was held in Cortina, Italy to develop a consensus defining the
criteria for cure of acromegaly. The workshop was sponsored by the University of Brescia …
criteria for cure of acromegaly. The workshop was sponsored by the University of Brescia …
American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly-2011 update
L Katznelson, JLD Atkinson, DM Cook… - Endocrine …, 2011 - endocrinepractice.org
AACE= American Association of Clinical Endocrinologists; BEL=“best evidence” level;
BMD= bone mineral density; CPAP= continuous positive airway pressure; CPG= clinical …
BMD= bone mineral density; CPAP= continuous positive airway pressure; CPG= clinical …
Clinical factors involved in the recurrence of pituitary adenomas after surgical remission: a structured review and meta-analysis
F Roelfsema, NR Biermasz, AM Pereira - Pituitary, 2012 - Springer
To study the currently available data of recurrence rates of functioning and nonfunctioning
pituitary adenomas following surgical cure and to analyze associated predisposing factors …
pituitary adenomas following surgical cure and to analyze associated predisposing factors …
Resistance to somatostatin analogs in acromegaly
A Colao, RS Auriemma, G Lombardi… - Endocrine …, 2011 - academic.oup.com
Somatostatin analogs (SA) are widely used in acromegaly, either as first-line or adjuvant
treatment after surgery. First-line treatment with these drugs is generally used in the patients …
treatment after surgery. First-line treatment with these drugs is generally used in the patients …
Acromegaly
S Melmed - The pituitary, 2017 - Elsevier
Acromegaly is caused by excess growth hormone (GH) secretion emanating from a
somatotroph adenoma. High GH and Insulin-like growth factor-1 (IGF-1) levels lead to acral …
somatotroph adenoma. High GH and Insulin-like growth factor-1 (IGF-1) levels lead to acral …
Surgical management of GH-secreting pituitary adenomas: an outcome study using modern remission criteria
J Kreutzer, ML Vance, MBS Lopes… - The Journal of Clinical …, 2001 - academic.oup.com
The results of transsphenoidal surgery as initial therapy for GH-secreting pituitary adenomas
in 57 acromegalic patients were analyzed retrospectively. Patients with prior surgery or …
in 57 acromegalic patients were analyzed retrospectively. Patients with prior surgery or …
Free insulin-like growth factors–measurements and relationships to growth hormone secretion and glucose homeostasis
J Frystyk - Growth Hormone & IGF Research, 2004 - Elsevier
IGF-I is a multipotent growth factor with important actions on normal tissue growth and
regeneration. In addition, IGF-I has been suggested to have beneficial effects on glucose …
regeneration. In addition, IGF-I has been suggested to have beneficial effects on glucose …
Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly
J Ayuk, RN Clayton, G Holder… - The Journal of …, 2004 - academic.oup.com
Increased mortality in patients with acromegaly has been confirmed in a number of
retrospective studies, but causative factors and relationship to serum IGF-I remain uncertain …
retrospective studies, but causative factors and relationship to serum IGF-I remain uncertain …