Recent Advances in Positron Emission Tomography Radiotracers to Image Cardiac Amyloidosis

AJ Romero Pabón, OF Clerc, S Vijayakumar… - Current Cardiology …, 2024 - Springer
Cardiac amyloidosis includes a group of protein-misfolding diseases characterized by fibril
accumulation within the extracellular space of the myocardium and cardiac dysfunction …

Prevalence of transthyretin amyloidosis among heart failure patients with preserved ejection fraction in Japan

T Naito, K Nakamura, Y Abe, H Watanabe… - ESC Heart …, 2023 - Wiley Online Library
Aims Heart failure with preserved ejection fraction (HFpEF), which is caused by wide various
conditions, has become a major public health problem. Transthyretin amyloid …

The right heart in patients with cancer. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Council of Cardio‐Oncology

K Keramida, D Farmakis, A Rakisheva… - European Journal of …, 2024 - Wiley Online Library
Cardio-oncology guidelines, position statements and clinical trials have focused on the
cardiotoxic effects of cancer therapies upon the left ventricle (LV)(1, 2). However, cancer …

Hemodynamic profiling and prognosis in cardiac amyloidosis

P Martens, S Bhattacharya, J Longinow… - Circulation: Heart …, 2023 - Am Heart Assoc
Background: Little information is available on the prognostic relevance of cardiac
hemodynamic cutoffs in cardiac amyloidosis (CA) and its subtypes. Methods: Consecutive …

Right ventricular free wall strain predicts transthyretin amyloidosis prognosis as well as biomarker-based staging systems

S Istratoaie, C Bourg, KC Lee, B Marut… - European Heart …, 2024 - academic.oup.com
Aims The diagnosis of transthyretin amyloidosis (ATTR) significantly impacts the
management and prognosis of patients initially presenting with heart failure (HF). Despite …

Prevalence and clinical significance of right ventricular pulmonary arterial uncoupling in cardiac amyloidosis

G Palmiero, E Monda, F Verrillo, F Dongiglio… - International Journal of …, 2023 - Elsevier
Background This study aims to evaluate the prevalence and the clinical significance of the
right ventricular pulmonary arterial (RV-PA) uncoupling in patients with cardiac amyloidosis …

Prognostic mortality factors in advanced light chain cardiac amyloidosis: A prospective cohort study

A Zaroui, M Kharoubi, R Gounot, S Oghina… - ESC Heart …, 2024 - Wiley Online Library
Aims Predicting mortality in severe AL cardiac amyloidosis is challenging due to elevated
biomarker levels and limited thresholds for stratifying severe cardiac damage. Methods and …

Quantification of right ventricular amyloid burden with 18F-florbetapir positron emission tomography/computed tomography and its association with right ventricular …

Y Datar, OF Clerc, SAM Cuddy, S Kim… - European Heart …, 2024 - academic.oup.com
Aims In systemic light-chain (AL) amyloidosis, quantification of right ventricular (RV) amyloid
burden has been limited and the pathogenesis of RV dysfunction is poorly understood …

Invasive haemodynamics at rest and exercise in cardiac amyloidosis

MF Holt, A Flø, H Ravnestad, V Bjørnø… - ESC Heart …, 2024 - Wiley Online Library
Aims Our aim was to investigate haemodynamics at rest and during exercise in patients with
transthyretin cardiomyopathy (ATTR‐CM) in light of the 2022 European Society of …

Levosimendan in cardiac amyloidosis: Unveiling promising paths

A Faggiano, S Carugo… - International …, 2024 - internationaljournalofcardiology.com
Cardiac amyloidosis (CA) is a progressive infiltrative disease primarily caused by the
accumulation of misfolded, cleaved, and aggregated proteins in the extracellular space of …