Targeted treatment for unresectable EGFR mutation-positive stage III non-small cell lung cancer: Emerging evidence and future perspectives

T Kato, I Casarini, M Cobo, C Faivre-Finn… - Lung Cancer, 2024 - Elsevier
Epidermal growth factor receptor (EGFR) mutations are detected in up to one third of
patients with unresectable stage III non-small cell lung cancer (NSCLC). The current …

Stereotactic body radiation therapy in unresectable stage III non-small cell lung cancer: A systematic review

B Allignet, D De Ruysscher, I Martel-Lafay… - Cancer Treatment …, 2023 - Elsevier
In unresectable stage III non-small cell lung cancer (NSCLC), the standard of care for most fit
patients is concurrent chemotherapy with normofractionated radiotherapy (NFRT), followed …

Comparison of post-chemoradiotherapy pneumonitis between Asian and non-Asian patients with locally advanced non-small cell lung cancer: a systematic review …

T Liu, S Li, S Ding, J Qiu, C Ren, J Chen, H Wang… - …, 2023 - thelancet.com
Background Pneumonitis is a common complication for patients with locally advanced non-
small cell lung cancer undergoing definitive chemoradiotherapy (CRT). It remains unclear …

Clinical implications of the serum platelet-to-lymphocyte ratio in the modern radiation oncology era: research update and literature review

DS Lee - Radiation Oncology, 2024 - Springer
Radiation therapy (RT) continues to be the primary approach for treating cancer, and
numerous cancer biomarkers associated with oncological outcomes have been investigated …

International Cost-Effectiveness Analysis of Durvalumab in Stage III Non–Small Cell Lung Cancer

SA Kareff, S Han, B Haaland, CJ Jani, R Kohli… - JAMA Network …, 2024 - jamanetwork.com
Importance Standard of care for unresectable locally advanced non–small cell lung cancer
(NSCLC) involves definitive chemoradiotherapy followed by maintenance therapy with …

Management of oncogene driven locally advanced unresectable non-small cell lung cancer

J Loh, JL Low, M Sachdeva, PQJ Low… - Expert Review of …, 2023 - Taylor & Francis
Introduction The current standard of care of locally advanced non-small cell lung cancer (LA-
NSCLC) is concurrent chemoradiation, followed by consolidation durvalumab. However …

Pneumonitis risk after chemoradiotherapy with and without immunotherapy in patients with locally advanced non-small cell lung cancer: A systematic review and meta …

C Han, J Qiu, L Bai, T Liu, J Chen, H Wang… - International Journal of …, 2024 - Elsevier
Purpose Chemoradiotherapy (CRT) combined with immune checkpoint inhibitors (ICIs) is
the standard of care for patients with unresectable and locally advanced non-small cell lung …

Derived neutrophil-to-lymphocyte ratio has the potential to predict safety and outcomes of durvalumab after chemoradiation in non-small cell lung cancer

A Sugimoto, H Kaneda, N Yoshimoto, K Nagata… - Scientific Reports, 2024 - nature.com
The usefulness of the derived neutrophil-to-lymphocyte ratio (dNLR) and its dynamics
before/after durvalumab consolidation therapy to predict safety or efficacy remains unclear …

Durvalumab after chemoradiotherapy in patients with stage III non-small-cell lung cancer: real-world outcomes versus clinical trial results

MV Verschueren, T Dijs, JL Gulikers, A Veelen… - …, 2023 - Taylor & Francis
Aim: We investigated the effectiveness of durvalumab post-concurrent CRT (cCRT) and post-
sequential CRT (sCRT) versus cCRT and sCRT alone and compared these outcomes with …

A propensity-matched retrospective comparative study with historical control to determine the real-world effectiveness of durvalumab after concurrent …

CK Park, N Jeon, HK Park, HJ Oh, YC Kim, HL Jeon… - Cancers, 2023 - mdpi.com
Simple Summary The PACIFIC trial demonstrated the survival benefits of durvalumab
consolidation (DC) in patients with unresectable stage III non–small cell lung cancer …