Transplantation is an effective approach for treating end-stage organ failure. There has been
a long-standing interest in xenotransplantation as a means of increasing the number of …

Human islet transplantations into rodent models are an essential tool to aid in the
development and testing of islet and cellular-based therapies for diabetes prevention and …

Pig islet xenotransplantation is a potential treatment for patients with type 1 diabetes.
Current efforts are focused on identifying the optimal pig islet source and overcoming the …

Background Islet transplantation is a promising minimally invasive approach that dispenses
with many challenges, especially immunological complications such as instant blood …

Für Typ-1-Diabetes-Patienten, die trotz Optimierung der Insulintherapie an rezidivierenden
lebensbedrohlichen Hypoglykämien leiden, ist die Inselzelltransplantation die beste …

Transplantation of purified human pancreatic islets has become a viable treatment option for
selected patients with type 1 diabetes. Phase III trials have documented the efficacy and …

The number of preclinical studies that use drugs or endogenous factors for various
targetable sites aiming to improve islet function and engraftment has recently gained more …