Ceramic bone implants have potential properties ideal for long-term implantation
applications. On comparison with other materials, ceramic biomaterials have advantages …

Oxygen is critical to the survival, function and fate of mammalian cells. Oxygen tension
controls cellular behavior through metabolic programming, which in turn controls tissue …

Large bone defects resulting from fractures and disease are a major clinical challenge,
being often unable to heal spontaneously by the body's repair mechanisms. Lines of …

Titanium-based implants often lead to premature implant failure due to the lack of
antimicrobial, osteogenic, and angiogenic properties. To this end, a new strategy was …

Abnormal levels of reactive oxygen species (ROS) and the hypoxic microenvironment within
bone defects are important factors that impede bone repair processes. Herein, an innovative …

Hypoxic nonhealing wounds are a common complication in chronic patients, and chronic
hypoxia is the main reason for delayed wound healing, so local wound oxygenation may be …

The lack of oxygen supply in engineered constructs has been an ongoing challenge for
tissue engineering and regenerative medicine. Upon implantation of an engineered tissue …

Bone tissue engineering is a field to manufacture scaffolds for bone defects that cannot
repair without medical interventions. Ceramic nanoparticles such as bredigite have …

Supplying sufficient oxygen within the scaffolds is one of the essential hindrances in tissue
engineering that can be resolved by oxygen‐generating biomaterials (OGBs). Two main …

Homogeneous vascularization of implanted tissue constructs can extend to 5 weeks, during
which cell death can occur due to inadequate availability of oxygen. Researchers are …