Epoxides: Developability as active pharmaceutical ingredients and biochemical probes
B Kaur, P Singh - Bioorganic Chemistry, 2022 - Elsevier
Epoxide functional group is a part of several natural as well as synthetic compounds.
Irrespective of the role of epoxide group in drug efficacy and the use of epoxide compounds …
Irrespective of the role of epoxide group in drug efficacy and the use of epoxide compounds …
[HTML][HTML] Progress and prediction of multicomponent quantification in complex systems with practical LC-UV methods
X Chen, Z Yang, Y Xu, Z Liu, Y Liu, Y Dai… - Journal of Pharmaceutical …, 2023 - Elsevier
Complex systems exist widely, including medicines from natural products, functional foods,
and biological samples. The biological activity of complex systems is often the result of the …
and biological samples. The biological activity of complex systems is often the result of the …
Single-cell adhesion force kinetics of cell populations from combined label-free optical biosensor and robotic fluidic force microscopy
Single-cell adhesion force plays a crucial role in biological sciences, however its in-depth
investigation is hindered by the extremely low throughput and the lack of temporal resolution …
investigation is hindered by the extremely low throughput and the lack of temporal resolution …
[HTML][HTML] Comprehensive review on the interaction between natural compounds and brain receptors: Benefits and toxicity
AR Silva, C Grosso, C Delerue-Matos… - European journal of …, 2019 - Elsevier
Given their therapeutic activity, natural products have been used in traditional medicines
throughout the centuries. The growing interest of the scientific community in …
throughout the centuries. The growing interest of the scientific community in …
Offline preparative three-dimensional HPLC for systematic and efficient purification of alkaloids from Gelsemium elegans Benth
D Liu, Y Han, H Zhou, H Jin, H Kang, FF Huang… - … of Chromatography A, 2021 - Elsevier
The natural compound library is the most productive source in drug discovery and alkaloids
are the most potential drug leads in natural compounds. Presently, systematic purification of …
are the most potential drug leads in natural compounds. Presently, systematic purification of …
Anisotanols A—D, Four Norsesquiterpenoids with an Unprecedented Sesquiterpenoid Skeleton from Anisodus tanguticus‡
HY Zhao, QM Zhou, H Zhu, F Zhou… - Chinese Journal of …, 2021 - Wiley Online Library
Main observation and conclusion Anisotanols A—D (1—4), four new compounds
possessing an unprecedented sesquiterpenoid skeleton with a congested tricyclic 6/3/5 ring …
possessing an unprecedented sesquiterpenoid skeleton with a congested tricyclic 6/3/5 ring …
Characterization of tropane and cinnamamide alkaloids from Scopolia tangutica by high‐performance liquid chromatography with quadrupole time‐of‐flight tandem …
Scopolia tangutica is a traditional Chinese medicine used for antispasmodic, anesthesia,
analgesia, and sedation. Its medicinal activity is associated to alkaloid constituents …
analgesia, and sedation. Its medicinal activity is associated to alkaloid constituents …
Preparative separation of four isomers of synthetic anisodamine by HPLC and diastereomer crystallization
T Wu, JX Zhu, Q Wei, P Li, LB Wang, J Huang… - Chirality, 2019 - Wiley Online Library
Abstract Anisodamine (654‐1), a well‐known cholinergic antagonist, is marketed as
synthetic anisodamine (mixture of four isomers, 654‐2) in China. To preparative resolution …
synthetic anisodamine (mixture of four isomers, 654‐2) in China. To preparative resolution …
New amides from the roots of Anisodus tanguticus
HY Zhao, J Liu, H Zhu, F Liu, ZH Liu, C Peng… - … Systematics and Ecology, 2020 - Elsevier
Abstract Two new amides (1 and 2) and four known analogues (3–6) were isolated from the
roots of Anisodus tanguticus (Maxim.) Pascher. Their structures were determined by …
roots of Anisodus tanguticus (Maxim.) Pascher. Their structures were determined by …
Traditional Tibetan medicinal plants: a highlighted resource for novel therapeutic compounds
DC Hao, PG Xiao, C Liu - Future Medicinal Chemistry, 2018 - Taylor & Francis
Around 70–80% of drugs used in traditional Tibetan medicine (TTM) come from Qinghai
Tibet Plateau, the majority of which are plants. The biological and medicinal culture diversity …
Tibet Plateau, the majority of which are plants. The biological and medicinal culture diversity …