Influence of the mechanical environment on the regeneration of osteochondral defects

S Davis, M Roldo, G Blunn, G Tozzi… - … in Bioengineering and …, 2021 - frontiersin.org
Articular cartilage is a highly specialised connective tissue of diarthrodial joints which
provides a smooth, lubricated surface for joint articulation and plays a crucial role in the …

Preparation of large biological samples for high-resolution, hierarchical, synchrotron phase-contrast tomography with multimodal imaging compatibility

J Brunet, CL Walsh, WL Wagner, A Bellier, C Werlein… - Nature protocols, 2023 - nature.com
Imaging across different scales is essential for understanding healthy organ morphology
and pathophysiological changes. The macro-and microscale three-dimensional morphology …

Digital image and volume correlation with X-ray micro-computed tomography for deformation and damage characterisation of woven fibre-reinforced composites

J Holmes, S Sommacal, Z Stachurski, R Das… - Composite …, 2022 - Elsevier
Woven composites have complex deformation and damage behaviour which surface-based
characterisation methods struggle to capture. This work combines surface digital image …

Identification of an ultrathin osteochondral interface tissue with specific nanostructure at the human knee joint

X Wang, J Lin, Z Li, Y Ma, X Zhang, Q He, Q Wu… - Nano Letters, 2022 - ACS Publications
Cartilage adheres to subchondral bone via a specific osteochondral interface tissue where
forces are transferred from soft cartilage to hard bone without conferring fatigue damage …

Digital volume correlation for the characterization of musculoskeletal tissues: Current challenges and future developments

E Dall'Ara, G Tozzi - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
Biological tissues are complex hierarchical materials, difficult to characterise due to the
challenges associated to the separation of scale and heterogeneity of the mechanical …

Rational design of soft–hard interfaces through bioinspired engineering

H Zhang, Y Ma, Y Wang, L Niu, R Zou, M Zhang, H Liu… - Small, 2023 - Wiley Online Library
Soft–hard tissue interfaces in nature present a diversity of hierarchical transitions in
composition and structure to address the challenge of stress concentrations that would …

Imaging Cu2O nanocube hollowing in solution by quantitative in situ X-ray ptychography

L Grote, M Seyrich, R Döhrmann… - Nature …, 2022 - nature.com
Understanding morphological changes of nanoparticles in solution is essential to tailor the
functionality of devices used in energy generation and storage. However, we lack …

Stage-specific and location-specific cartilage calcification in osteoarthritis development

X Wang, Q Wu, R Zhang, Z Fan, W Li, R Mao… - Annals of the …, 2023 - ard.bmj.com
Objectives This study investigated the stage-specific and location-specific deposition and
characteristics of minerals in human osteoarthritis (OA) cartilages via multiple nano …

[HTML][HTML] A practical guide for in situ mechanical testing of musculoskeletal tissues using synchrotron tomography

E Dall'Ara, AJ Bodey, H Isaksson, G Tozzi - journal of the mechanical …, 2022 - Elsevier
Musculoskeletal tissues are complex hierarchical materials where mechanical response is
linked to structural and material properties at different dimensional levels. Therefore, high …

[HTML][HTML] Nonlinear micro finite element models based on digital volume correlation measurements predict early microdamage in newly formed bone

MP Fernández, SJ Sasso, S McPhee, C Black… - journal of the …, 2022 - Elsevier
Bone regeneration in critical-sized defects is a clinical challenge, with biomaterials under
constant development aiming at enhancing the natural bone healing process. The delivery …