Simple Summary Infections with Hepatitis B and Hepatitis C viruses are usually
asymptomatic and although some patients undergo resolution of infection, the majority do …

A severe course has been described in early studies on chronic hepatitis D (CHD), with
faster pace towards liver cirrhosis with subsequent high liver‐related morbidity and mortality …

Accumulation of activated immune cells results in nonspecific hepatocyte killing in chronic
hepatitis B (CHB), leading to fibrosis and cirrhosis. This study aims to understand the …

Background & Aims Bulevirtide is a first-in-class entry inhibitor of hepatitis B surface antigen.
In July 2020, bulevirtide was conditionally approved for the treatment of hepatitis D, the most …

Background & Aims Pyruvate dehydrogenase (PDC)-E2 specific CD8+ T cells play a leading
role in biliary destruction in PBC. However, there are limited data on the characterization of …

Bulevirtide recently received conditional approval from the EMA for the treatment of chronic
hepatitis delta, but the ideal duration of therapy is unknown. Herein, we describe the first …

Although many viral infections are linked to the development of neurological disorders, the
mechanism governing virus-induced neuropathology remains poorly understood …

More than twenty years ago, non–HBV-specific CD8+ T cells were found to contribute to liver
immunopathology in chronic HBV infection, while HBV-specific CD8+ T cells were noted to …

Tissue-resident memory (TRM) T cells are a unique subset of memory T cells that are critical
for the first line of defense against pathogens or antigens in peripheral non-lymphoid tissues …

Background and aims The co-infection of hepatitis B (HBV) patients with the hepatitis D virus
(HDV) causes the most severe form of viral hepatitis and thus drastically worsens the course …