Nonalcoholic fatty liver disease and insulin resistance: new insights and potential new treatments

H Kitade, G Chen, Y Ni, T Ota - Nutrients, 2017 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders
worldwide. It is associated with clinical states such as obesity, insulin resistance, and type 2 …

[HTML][HTML] Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity

ML Bonet, JA Canas, J Ribot, A Palou - Archives of biochemistry and …, 2015 - Elsevier
A novel perspective of the function of carotenoids and carotenoid-derived products−
including, but not restricted to, the retinoids− is emerging in recent years which connects …

Roles of chemokines and chemokine receptors in obesity-associated insulin resistance and nonalcoholic fatty liver disease

L Xu, H Kitade, Y Ni, T Ota - Biomolecules, 2015 - mdpi.com
Abundant evidence has demonstrated that obesity is a state of low-grade chronic
inflammation that triggers the release of lipids, aberrant adipokines, pro-inflammatory …

Carotenoids in the treatment of diabetes mellitus and its complications: A mechanistic review

A Roohbakhsh, G Karimi, M Iranshahi - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Carotenoids are a large class of natural antioxidants that occur in many vegetables, foods
and other natural sources. To date, a large number of biological properties have been …

Intake of fruit, vegetables, and antioxidants and risk of type 2 diabetes: systematic review and meta-analysis

M Hamer, Y Chida - Journal of hypertension, 2007 - journals.lww.com
Background The public health recommendation is to consume five or more servings of fruit
and vegetables daily, but the association between the intake of fruit and vegetables and the …

[HTML][HTML] The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis

ETM Leermakers, SKL Darweesh, CP Baena… - The American journal of …, 2016 - Elsevier
Background: The antioxidant lutein is suggested as being beneficial to cardiometabolic
health because of its protective effect against oxidative stress, but evidence has not …

Lycopene and cardiovascular diseases: an update

A Mordente, B Guantario, E Meucci… - Current medicinal …, 2011 - ingentaconnect.com
Cardiovascular disease (CVD) is the leading cause of death in Western societies and
accounts for up to a third of all deaths worldwide. In comparison to the Northern European or …

Chemistry, stability, and biological actions of carotenoids

EM Yahia, J de Jesús Ornelas‐Paz… - Fruit and Vegetable …, 2017 - Wiley Online Library
A striking characteristic of the carotenoid structure is the long system of alternating double
and single bonds that forms the central part of the molecule. Physical properties, natural …

Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with lower presence of non-alcoholic fatty liver disease in middle-aged and …

ML Xiao, JS Lin, YH Li, M Liu, YY Deng… - Public health …, 2020 - cambridge.org
Objective: Previous studies have shown that the Dietary Approaches to Stop Hypertension
(DASH) diet might contribute to managing risk factors of non-alcoholic fatty liver disease …

Carotenoids in drug discovery and medicine: pathways and molecular targets implicated in human diseases

DS Metibemu, IV Ogungbe - Molecules, 2022 - mdpi.com
Carotenoids are isoprenoid-derived natural products produced in plants, algae, fungi, and
photosynthetic bacteria. Most animals cannot synthesize carotenoids because the …