Crystal engineering of pharmaceutical cocrystals in the discovery and development of improved drugs

G Bolla, B Sarma, AK Nangia - Chemical reviews, 2022 - ACS Publications
The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

Eutectics: formation, properties, and applications

D Yu, Z Xue, T Mu - Chemical Society Reviews, 2021 - pubs.rsc.org
Various eutectic systems have been proposed and studied over the past few decades. Most
of the studies have focused on three typical types of eutectics: eutectic metals, eutectic salts …

Covalent organic framework atropisomers with multiple gas-triggered structural flexibilities

C Kang, Z Zhang, S Kusaka, K Negita, AK Usadi… - Nature Materials, 2023 - nature.com
Covalent organic frameworks (COFs) are emerging crystalline porous polymers, showing
great potential for applications but lacking gas-triggered flexibility. Atropisomerism was …

Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Creating cocrystals: A review of pharmaceutical cocrystal preparation routes and applications

M Karimi-Jafari, L Padrela, GM Walker… - Crystal Growth & …, 2018 - ACS Publications
Originally discovered almost a century ago, cocrystals continue to gain interest in the
modern day due to their ability to modify the physical properties of solid-state materials …

Interface engineering in organic field-effect transistors: principles, applications, and perspectives

H Chen, W Zhang, M Li, G He, X Guo - Chemical reviews, 2020 - ACS Publications
Heterogeneous interfaces that are ubiquitous in optoelectronic devices play a key role in the
device performance and have led to the prosperity of today's microelectronics. Interface …

Cocrystal engineering: a collaborative strategy toward functional materials

L Sun, Y Wang, F Yang, X Zhang, W Hu - Advanced Materials, 2019 - Wiley Online Library
Cocrystal engineering with a noncovalent assembly feature by simple constituent units has
inspired great interest and has emerged as an efficient and versatile route to construct …

Organic semiconductor single crystals for electronics and photonics

X Zhang, H Dong, W Hu - Advanced Materials, 2018 - Wiley Online Library
Organic semiconducting single crystals (OSSCs) are ideal candidates for the construction of
high‐performance optoelectronic devices/circuits and a great platform for fundamental …

Recent advances of cocrystals with room temperature phosphorescence

M Singh, K Liu, S Qu, H Ma, H Shi, Z An… - Advanced Optical …, 2021 - Wiley Online Library
Organic phosphorescent materials have attracted wide attention in recent years owing to
their opportunities in various functional applications. Through appropriate molecular design …

Pharmaceutical cocrystals: along the path to improved medicines

NK Duggirala, ML Perry, Ö Almarsson… - Chemical …, 2016 - pubs.rsc.org
Cocrystals, a long known but understudied class of crystalline solids, have attracted interest
from crystal engineers and pharmaceutical scientists in the past decade and are now an …