Cytoplasmic dynein 1 is an important microtubule-based motor in many eukaryotic cells.
Dynein has critical roles both in interphase and during cell division. Here, we focus on …

Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …

The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental
cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways …

This paper presents a computationally efficient, two-dimensional, feature point tracking
algorithm for the automated detection and quantitative analysis of particle trajectories as …

To track the behavior of human immunodeficiency virus (HIV)-1 in the cytoplasm of infected
cells, we have tagged virions by incorporation of HIV Vpr fused to the GFP. Observation of …

Adenoviruses have been studied intensively for over 50 years as models of virus–cell
interactions and latterly as gene vectors. With the advent of more sophisticated structural …

Influenza is a paradigm for understanding viral infections. As an opportunistic pathogen
exploiting the cellular endocytic machinery for infection, influenza is also a valuable model …

We describe a method, based on single-molecule imaging, that allows the real-time
visualization of the infection pathway of single viruses in living cells, each labeled with only …