Mechanisms of spermidine-induced autophagy and geroprotection

SJ Hofer, AK Simon, M Bergmann, T Eisenberg… - Nature aging, 2022 - nature.com
Aging involves the systemic deterioration of all known cell types in most eukaryotes. Several
recently discovered compounds that extend the healthspan and lifespan of model organisms …

Diabetes and hypertension: is there a common metabolic pathway?

BMY Cheung, C Li - Current atherosclerosis reports, 2012 - Springer
Diabetes and hypertension frequently occur together. There is substantial overlap between
diabetes and hypertension in etiology and disease mechanisms. Obesity, inflammation …

Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice

X Loyer, S Potteaux, AC Vion, CL Guérin… - Circulation …, 2014 - Am Heart Assoc
Rationale for Study: MicroRNAs (miRNAs) are small noncoding RNAs that regulate protein
expression at post-transcriptional level. We hypothesized that a specific pool of endothelial …

Role of hydrogen sulfide in the development of atherosclerotic lesions in apolipoprotein E knockout mice

Y Wang, X Zhao, H Jin, H Wei, W Li, D Bu… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—We explored the effect of hydrogen sulfide (H2S) on atherosclerotic progression,
particularly on intracellular adhesion molecule-1 (ICAM-1) in apolipoprotein-E knockout …

Dietary and endogenous sphingolipid metabolism in chronic inflammation

GH Norris, CN Blesso - Nutrients, 2017 - mdpi.com
Chronic inflammation is a common underlying factor in many major metabolic diseases
afflicting Western societies. Sphingolipid metabolism is pivotal in the regulation of …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

مقایسة اثر تمرین تناوبی شدید و مقاومتی فزاینده بر بیان ژن ATF3 عضلة قلبی موش‌های صحرایی دیابتی نر

سفال منش, شهاب الدین, خالدی, ندا, رجبی… - نشریه فیزیولوژی ورزش و …, 2021‎ - joeppa.sbu.ac.ir
هدف: از سازوکارهای مؤثر در انجام بهتر عملکرد عضلانی در ورزشکاران، القای ظرفیت
پیش‌فعال‌سازی (PAP) در روش گرم کردن است. ازاین‌رو، پژوهش حاضر به‌منظور بررسی تأثیر گرم …

Endothelial inflammation and neutrophil transmigration are modulated by extracellular matrix composition in an inflammation-on-a-chip model

RB Riddle, K Jennbacken, KM Hansson, MT Harper - Scientific Reports, 2022 - nature.com
Inflammatory diseases are often characterised by excessive neutrophil infiltration from the
blood stream to the site of inflammation, which damages healthy tissue and prevents …

Relationships of circulating carotenoid concentrations with several markers of inflammation, oxidative stress, and endothelial dysfunction: the Coronary Artery Risk …

A Hozawa, DR Jacobs Jr, MW Steffes… - Clinical …, 2007 - academic.oup.com
Background: Serum carotenoid concentrations relate inversely to cardiovascular disease
incidence. To clarify the effect of carotenoids on atherosclerotic risk factors, we examined the …

Dysregulated long non-coding RNA in Sjögren's disease impacts both interferon and adaptive immune responses

ML Joachims, B Khatri, C Li, KL Tessneer, JA Ice… - RMD open, 2022 - rmdopen.bmj.com
Objective Sjögren's disease (SjD) is an autoimmune disease characterised by inflammatory
destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjDRo+) exhibit …