MicroRNAs‐mediated regulation of skeletal muscle GLUT4 expression and translocation in insulin resistance
JV Esteves, FJ Enguita… - Journal of diabetes …, 2017 - Wiley Online Library
The solute carrier family 2 facilitated glucose transporter member 4 (GLUT4) plays a key role
in the insulin‐induced glucose uptake by muscle and adipose tissues. In prediabetes and …
in the insulin‐induced glucose uptake by muscle and adipose tissues. In prediabetes and …
Endothelial cells as key players in cerebral small vessel disease
R Kremer, A Williams, J Wardlaw - Nature Reviews Neuroscience, 2025 - nature.com
Cerebral small vessel disease (SVD) is a vascular disorder that increases the risk of stroke
and dementia and is diagnosed through brain MRI. Current primary prevention and …
and dementia and is diagnosed through brain MRI. Current primary prevention and …
Proposed mechanism for understanding the dose-and time-dependency of the effects of fluoride in the liver
Fluoride (F) can induce changes in the expression of several liver proteins. It is suggested
that these changes are dose-and time-dependent. The objective of this study was to analyze …
that these changes are dose-and time-dependent. The objective of this study was to analyze …
SGLT1 activity in lung alveolar cells of diabetic rats modulates airway surface liquid glucose concentration and bacterial proliferation
TL Oliveira, N Candeia-Medeiros… - Scientific reports, 2016 - nature.com
High glucose concentration in the airway surface liquid (ASL) is an important feature of
diabetes that predisposes to respiratory infections. We investigated the role of alveolar …
diabetes that predisposes to respiratory infections. We investigated the role of alveolar …
miR-335-5p aggravates type 2 diabetes by inhibiting SLC2A4 expression
G Li, L Zhang - Biochemical and Biophysical Research …, 2021 - Elsevier
Abstract Globally, type 2 diabetes (T2D) is the most common chronic disease. It affects
approximately 500 million people worldwide. Dysregulation of the solute carrier family 2 …
approximately 500 million people worldwide. Dysregulation of the solute carrier family 2 …
Resveratrol improves glycemic control in insulin-treated diabetic rats: participation of the hepatic territory
Background Resveratrol is a natural polyphenol that has been proposed to improve
glycemic control in diabetes, by mechanisms that involve improvement in insulin secretion …
glycemic control in diabetes, by mechanisms that involve improvement in insulin secretion …
Diabetes induces tri-methylation at lysine 9 of histone 3 at Slc2a4 gene in skeletal muscle: A new target to improve glycemic control
Expression of the glucose transporter GLUT4, encoded by Slc2a4 gene, is reduced in both
type 1 and type 2 diabetes (T1D and T2D), contributing to glycemic impairment. The present …
type 1 and type 2 diabetes (T1D and T2D), contributing to glycemic impairment. The present …
[HTML][HTML] Insulin induces steroidogenesis in canine luteal cells via PI3K-MEK-MAPK
RS Silva, APMM Cardoso, IC Giometti, L D'Aprile… - Molecular and Cellular …, 2022 - Elsevier
Glucose uptake increases in canine luteal cells under insulin treatment. We hypothesize that
insulin also increases luteal cell steroidogenesis. Dogs underwent elective …
insulin also increases luteal cell steroidogenesis. Dogs underwent elective …
[HTML][HTML] The influence of hypertensive environment on adipose tissue remodeling measured by fluorescence lifetime imaging in spontaneously hypertensive rats
There is a lack of information correlating low adiposity with hypertension experienced by
Spontaneous Hypertensive Rats (SHR) or overweight and normotension in Wistar-Kyoto …
Spontaneous Hypertensive Rats (SHR) or overweight and normotension in Wistar-Kyoto …
Beta-adrenergic blockade increases GLUT4 and improves glycemic control in insulin-treated diabetic Wistar rats
Objective Unequivocal modulation of glycemic homeostasis by chronic beta-adrenergic
blockade in diabetes has never been demonstrated. This study investigates the participation …
blockade in diabetes has never been demonstrated. This study investigates the participation …