Inflammation context in Alzheimer's disease, a relationship intricate to define
C Novoa, P Salazar, P Cisternas, C Gherardelli… - Biological Research, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …
Oxidative stress in the tumor microenvironment and its relevance to cancer immunotherapy
NS Aboelella, C Brandle, T Kim, ZC Ding, G Zhou - Cancers, 2021 - mdpi.com
Simple Summary Cancer cells are consistently under oxidative stress, as reflected by
elevated basal level of reactive oxygen species (ROS), due to increased metabolism driven …
elevated basal level of reactive oxygen species (ROS), due to increased metabolism driven …
Bio-oriented synthesis of novel (S)-flurbiprofen clubbed hydrazone schiff's bases for diabetic management: In vitro and in silico studies
A new series of (S)-flurbiprofen derivatives 4a–4p and 5a–5n were synthesized with different
aromatic or aliphatic aldehydes and ketones to produce Schiff's bases and their structures …
aromatic or aliphatic aldehydes and ketones to produce Schiff's bases and their structures …
Nonsteroidal anti-inflammatory drugs in ophthalmology
SJ Kim, AJ Flach, LM Jampol - Survey of ophthalmology, 2010 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are increasingly employed in ophthalmology
to reduce miosis and inflammation, manage scleritis, and prevent and treat cystoid macular …
to reduce miosis and inflammation, manage scleritis, and prevent and treat cystoid macular …
Cyclooxygenase inhibitors: from pharmacology to clinical read-outs
P Patrignani, C Patrono - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Acetylsalicylic acid (aspirin) is a prototypic cyclooxygenase (COX) inhibitor. It was
synthesized serendipitously from a natural compound, ie, salicylic acid, with known …
synthesized serendipitously from a natural compound, ie, salicylic acid, with known …
Molecular targets of aspirin and cancer prevention
L Alfonso, G Ai, RC Spitale, GJ Bhat - British journal of cancer, 2014 - nature.com
Salicylates from plant sources have been used for centuries by different cultures to treat a
variety of ailments such as inflammation, fever and pain. A chemical derivative of salicylic …
variety of ailments such as inflammation, fever and pain. A chemical derivative of salicylic …
Cyclooxygenase-2 (COX-2)–independent anticarcinogenic effects of selective COX-2 inhibitors
S Grösch, TJ Maier, S Schiffmann… - Journal of the National …, 2006 - academic.oup.com
Nonsteroidal antiinflammatory drugs (NSAIDs) appear to reduce the risk of developing
cancer. One mechanism through which NSAIDs act to reduce carcinogenesis is to inhibit the …
cancer. One mechanism through which NSAIDs act to reduce carcinogenesis is to inhibit the …
[HTML][HTML] Colorectal carcinogenesis: Review of human and experimental animal studies
T Tanaka - Journal of carcinogenesis, 2009 - ncbi.nlm.nih.gov
This review gives a comprehensive overview of cancer development and links it to the
current understanding of tumorigenesis and malignant progression in colorectal cancer. The …
current understanding of tumorigenesis and malignant progression in colorectal cancer. The …
The role of inflammation in colon cancer
NB Janakiram, CV Rao - Inflammation and cancer, 2014 - Springer
Colorectal cancer (CRC) is the one of the leading causes of cancer-related deaths in the
world. CRC is responsible for more than 600,000 deaths annually and incidence rates are …
world. CRC is responsible for more than 600,000 deaths annually and incidence rates are …
Metal complexes of NSAIDs as potent anti-tumor chemotherapeutics: Mechanistic insights into cytotoxic activity via multiple pathways primarily by inhibition of COX–1 …
Non–steroidal anti-inflammatory drugs (NSAIDs) have gained considerable attention due to
their well–established medicinal properties such as anti-inflammatory, anti-bacterial, anti …
their well–established medicinal properties such as anti-inflammatory, anti-bacterial, anti …