Introduction Despite clear guidelines recommendations, most patients with heart failure and
reduced ejection–fraction (HFrEF) do not attain guideline-recommended target doses. We …

Adverse remodelling following an initial insult is the hallmark of heart failure (HF)
development and progression. It is manifested as changes in size, shape, and function of the …

With the emergence of cardiac resynchronization therapy (CRT) as a powerful tool to
reverse left ventricular dysfunction in patients with left bundle branch block (LBBB), there is …

Background An important number of patients with idiopathic dilated cardiomyopathy have
dramatically improved left ventricular function with optimal treatment; however, little is known …

Aims To explore whether left ventricular reverse remodelling (LVRR) is a predictor of
outcomes in patients with functional mitral regurgitation (FMR) undergoing MitraClip …

Background Heart failure (HF) pharmacotherapy is often not prescribed according to
guidelines. This longitudinal study investigated prescription rates and dosages of …

Importance Improvement in left ventricular ejection fraction (EF) to> 35% occurs in many
patients with reduced EF at baseline. To our knowledge, whether implantable cardioverter …

Myocardial reverse remodeling has been reported to occur in 25–70% of patients with
dilated cardiomyopathy. It is not yet fully understood whether remodeling represents disease …

Background Although cardiac resynchronization therapy (CRT) is effective for some patients
with heart failure and a reduced left ventricular ejection fraction (HFrEF), evidence gaps …

Abstract Aims Sacubitril/valsartan (SAC/VAL) has been used in patients with heart failure
and reduced ejection fraction (HFrEF), and cardiac resynchronization therapy (CRT) could …