Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Cancer metabolism: looking forward
I Martínez-Reyes, NS Chandel - Nature Reviews Cancer, 2021 - nature.com
Tumour initiation and progression requires the metabolic reprogramming of cancer cells.
Cancer cells autonomously alter their flux through various metabolic pathways in order to …
Cancer cells autonomously alter their flux through various metabolic pathways in order to …
[PDF][PDF] Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
S Kumagai, S Koyama, K Itahashi, T Tanegashima… - Cancer Cell, 2022 - cell.com
The balance of programmed death-1 (PD-1)-expressing CD8+ T cells and regulatory T
(Treg) cells in the tumor microenvironment (TME) determines the clinical efficacy of PD-1 …
(Treg) cells in the tumor microenvironment (TME) determines the clinical efficacy of PD-1 …
Chemodynamic therapy via fenton and fenton‐like nanomaterials: strategies and recent advances
Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …
Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy
H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
Mito‐bomb: targeting mitochondria for cancer therapy
X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Enhanced chemodynamic therapy by Cu–Fe peroxide nanoparticles: tumor microenvironment-mediated synergistic Fenton reaction
An urgent need in chemodynamic therapy (CDT) is to achieve high Fenton catalytic
efficiency at small doses of CDT agents. However, simple general promotion of the Fenton …
efficiency at small doses of CDT agents. However, simple general promotion of the Fenton …
Revisiting the Warburg effect: historical dogma versus current understanding
P Vaupel, G Multhoff - The Journal of physiology, 2021 - Wiley Online Library
Contrary to Warburg's original thesis, accelerated aerobic glycolysis is not a primary,
permanent and universal consequence of dysfunctional or impaired mitochondria …
permanent and universal consequence of dysfunctional or impaired mitochondria …
[HTML][HTML] Photodynamic Therapy for the Treatment and Diagnosis of Cancer–A Review of the Current Clinical Status
G Gunaydin, ME Gedik, S Ayan - Frontiers in chemistry, 2021 - frontiersin.org
Photodynamic therapy (PDT) has been used as an anti-tumor treatment method for a long
time and photosensitizers (PS) can be used in various types of tumors. Originally, light is an …
time and photosensitizers (PS) can be used in various types of tumors. Originally, light is an …
[PDF][PDF] Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells
J Gu, J Zhou, Q Chen, X Xu, J Gao, X Li, Q Shao… - Cell reports, 2022 - cell.com
Regulatory T (Treg) cells play a vital role in maintaining the immunosuppressive tumor
microenvironment. Lactate is a crucial metabolite in cancer and is related to tumor …
microenvironment. Lactate is a crucial metabolite in cancer and is related to tumor …