Glycosylated polyene macrolides include effective antifungal agents, such as pimaricin,
nystatin, candicidin, and amphotericin B. For the treatment of systemic mycoses …

Several classes of ribosomally synthesized and post-translationally modified peptides
(RiPPs) are composed of multiple macrocycles. The enzymes that assemble these …

Trebouxia is the most common lichen-forming genus of aero-terrestrial green algae and all
its species are desiccation tolerant (DT). The molecular bases of this remarkable adaptation …

Cinnamoyl-containing nonribosomal peptides (CCNPs) constitute a unique family of natural
products. The enzyme mechanism for the biaryl phenol coupling reaction of the bicyclic …

A novel actinobacterium, strain YIM 96748T, was isolated from a saline soil sample collected
from the south bank of Aiding Lake in Xinjiang Province, Northwest China. Phylogenetic …

Microbial-derived products, while do not have many environmental side effects of their
synthetic counterparts, have proved more efficient than those synthetically obtained. The …

Four new efrotomycins, A1–A4 (1–4), were isolated from the salt mine-derived
Amycolatopsis cihanbeyliensis DSM 45679 and structurally determined. Efrotomycins A3 (3) …

A novel filamentous actinobacterium designated strain 4-36T showing broad-spectrum
antifungal activity was isolated from a coal mining site in Mongolia, and its taxonomic …

Three novel actinomycete strains, designated as DR6-1T, DR6-2 and DR6-4, isolated from
the roots of Dendrobium heterocarpum Lindl in Thailand were studied using a polyphasic …

Actinobacteria are ubiquitous, diverse, and one of the biggest lineages in the domain
Bacteria. Their existence has been documented in a variety of habitats, including terrestrial …