neuronal mechanisms releasing neurotransmitters, because antagonists of adrenalin,
acetylcholine, histamine and 5-hydroxytryptamine (5HT) did not affect the response to …

Tyrosine hydroxylase catalyzes the rate‐limiting step in the biosynthesis of the
catecholamines dopamine, norepinephrine, and epinephrine. Therefore, the regulation of …

THE molecular basis of target cell recognition by CD3− natural killer (NK) cells is poorly
understood, despite the ability of NK cells to lyse specific tumour cells1, 2. In general, target …

The rate‐limiting enzyme in catecholamine synthesis is tyrosine hydroxylase. It is
phosphorylated at serine (Ser) residues Ser8, Ser19, Ser31 and Ser40 in vitro, in situ and in …

α-Synuclein is an abundant presynaptic protein implicated in neuronal plasticity and
neurodegenerative diseases. Although the function of α-synuclein is not thoroughly …

Tetrahydrobiopterin-dependent systems occupy several interesting niches in biological
chemistry, as metalloproteins that activate O2 for highly specific oxidations, as regulators for …

The level of phosphorylation of any protein depends on the relative activities of protein
kinases and protein phosphatases (1), but the latter enzymes have received far less …

The protein phosphatases which dephosphorylate native, sarcoplasmic reticulum (SR)‐
associated phospholamban were studied in cardiac muscle extracts and in a Triton fraction …

Following the initial demonstration of phosphorylation of endogenous brain proteins
(Johnson et al., 1971), two decades of work have shown that this biochemical mechanism …

The aromatic amino acid hydroxylases phenylalanine hydroxylase, tyrosine hydroxylase,
and tryptophan hydroxylase are non-heme iron enzymes that catalyze key physiological …