[HTML][HTML] Alcohol-induced steatosis in liver cells

TM Donohue Jr - World journal of gastroenterology: WJG, 2007 - ncbi.nlm.nih.gov
Alcohol-induced fatty liver (steatosis) was believed to result from excessive generation of
reducing equivalents from ethanol metabolism, thereby enhancing fat accumulation. Recent …

Oxidative stress in alcoholic liver disease: role of NADPH oxidase complex

S De Minicis, DA Brenner - Journal of gastroenterology and …, 2008 - Wiley Online Library
Alcohol is a well‐known risk factor for liver damage and is one of the major causes of liver
disease worldwide. Chronic intake of alcohol, over a certain limit, inevitably leads to hepatic …

The Protective Effect of Hydroalcoholic Extract of Zingiber officinale Roscoe (Ginger) on Ethanol-Induced Reproductive Toxicity in Male Rats

A Akbari, K Nasiri, M Heydari… - Journal of evidence …, 2017 - journals.sagepub.com
This study was conducted to evaluate the prophylactic effect of ginger extract on ethanol-
induced reproductive toxicity in male rats. Twenty-eight adult male Sprague-Dawley rats …

Isotopomer analysis of lipid biosynthesis by high resolution mass spectrometry and NMR

AN Lane, TWM Fan, Z Xie, HNB Moseley… - Analytica chimica …, 2009 - Elsevier
We have coupled 2D-NMR and infusion FT-ICR-MS with computer-assisted assignment to
profile 13C-isotopologues of glycerophospholipids (GPL) directly in crude cell extracts …

[HTML][HTML] The FXR agonist 6ECDCA reduces hepatic steatosis and oxidative stress induced by ethanol and low-protein diet in mice

FAR Lívero, AM Stolf, AA Dreifuss… - Chemico-biological …, 2014 - Elsevier
Background and aim: Excessive ethanol consumption can lead to development of hepatic
steatosis. Since the FXR receptor regulates adipose cell function and liver lipid metabolism …

Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol‐induced steatosis

DV Avila, DF Barker, JW Zhang… - The Journal of …, 2016 - Wiley Online Library
Alcohol‐induced hepatic steatosis is a significant risk factor for progressive liver disease.
Cyclic adenosine monophosphate (cAMP) signalling has been shown to significantly …

Decreasing phosphatidylcholine on the surface of the lipid droplet correlates with altered protein binding and steatosis

L Listenberger, E Townsend, C Rickertsen, A Hains… - Cells, 2018 - mdpi.com
Alcoholic fatty liver disease (AFLD) is characterized by an abnormal accumulation of lipid
droplets (LDs) in the liver. Here, we explore the composition of hepatic LDs in a rat model of …

Role of transcription factors in steatohepatitis and hypertension after ethanol: the epicenter of metabolism

RA Ansari, K Husain, SAA Rizvi - Biomolecules, 2016 - mdpi.com
Chronic alcohol consumption induces multi-organ damage, including alcoholic liver disease
(ALD), pancreatitis and hypertension. Ethanol and ethanol metabolic products play a …

Alterations in hippocampal phospholipid profile by prenatal exposure to ethanol

Z Wen, HY Kim - Journal of Neurochemistry, 2004 - Wiley Online Library
It has been suggested that hippocampus‐related cognitive processes are especially
sensitive to ethanol. To provide an insight into the biochemical mechanisms underlying the …

Effect of Oral Administration of Weissella confusa on Fecal and Plasma Ethanol Concentrations, Lipids and Glucose Metabolism in Wistar Rats Fed High Fructose and …

FMF Elshaghabee, D Ghadimi… - Hepatic Medicine …, 2020 - Taylor & Francis
Background and Purpose In previous investigations, Weissella confusa was shown to lack
the metabolic pathway from fructose to mannitol and to produce ethanol when cultivated in …