Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis

Y Jiang, P Zhang, X Zhang, L Lv, Y Zhou - Cell proliferation, 2021 - Wiley Online Library
Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and
microstructural degeneration. The personal and societal costs of osteoporosis are …

Mesenchymal stem cells: amazing remedies for bone and cartilage defects

P Kangari, T Talaei-Khozani… - Stem Cell Research & …, 2020 - Springer
Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

Extracellular vesicles from adipose tissue‐derived stem cells alleviate osteoporosis through osteoprotegerin and miR‐21‐5p

KS Lee, J Lee, HK Kim, SH Yeom… - Journal of …, 2021 - Wiley Online Library
Osteoporosis is one of the most common skeletal disorders caused by the imbalance
between bone formation and resorption, resulting in quantitative loss of bone tissue. Since …

Mesenchymal stem cells: cell fate decision to osteoblast or adipocyte and application in osteoporosis treatment

L Hu, C Yin, F Zhao, A Ali, J Ma, A Qian - International Journal of …, 2018 - mdpi.com
Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …

Senile osteoporosis: the involvement of differentiation and senescence of bone marrow stromal cells

A Qadir, S Liang, Z Wu, Z Chen, L Hu… - International journal of …, 2020 - mdpi.com
Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …

Cellular senescence in skeletal disease: mechanisms and treatment

X He, W Hu, Y Zhang, M Chen, Y Ding, H Yang… - Cellular & Molecular …, 2023 - Springer
The musculoskeletal system supports the movement of the entire body and provides blood
production while acting as an endocrine organ. With aging, the balance of bone …

Natural history of mesenchymal stem cells, from vessel walls to culture vessels

IR Murray, CC West, WR Hardy, AW James… - Cellular and Molecular …, 2014 - Springer
Mesenchymal stem/stromal cells (MSCs) can regenerate tissues by direct differentiation or
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …

[HTML][HTML] Differentiation of bone marrow mesenchymal stem cells in osteoblasts and adipocytes and its role in treatment of osteoporosis

C Wang, H Meng, X Wang, C Zhao… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
Osteoporosis is a systemic metabolic bone disorder characterized by a decrease in bone
mass and degradation of the bone microstructure, leaving bones that are fragile and prone …

New frontiers in osteoporosis therapy

C Cheng, K Wentworth… - Annual Review of …, 2020 - annualreviews.org
Current osteoporosis medications reduce fractures significantly but have rare and serious
adverse effects (osteonecrosis of the jaw, atypical femoral fractures) that may limit their …

[HTML][HTML] Mesenchymal stem cell-associated lncRNA in osteogenic differentiation

C Ju, R Liu, YW Zhang, Y Zhang, R Zhou, J Sun… - Biomedicine & …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) have the ability to differentiate into multiple cell types,
including osteogenic, chondrogenic and adipogenic lineages. Osteogenic differentiation of …