Intestinal barrier dysfunction and dysbiosis contribute to development of diseases in liver
and other organs. Physical, immunologic, and microbiologic (bacterial, fungal, archaeal …

Liver diseases are caused by different etiological agents, mainly alcohol consumption,
viruses, drug intoxication or malnutrition. Frequently, liver diseases are initiated by oxidative …

In large amounts, alcohol and its metabolites can overwhelm the gastrointestinal tract (GI)
and liver and lead to damage both within the GI and in other organs. Specifically, alcohol …

Recent high-profile reports have reignited an interest in acetate metabolism in cancer. Acetyl-
CoA synthetases that catalyse the conversion of acetate to acetyl-CoA have now been …

Alcohol abuse disorder is a serious condition, implicating more than 15 million people aged
12 years and older in 2019 in the United States. Ethanol (or ethyl alcohol) is mainly oxidized …

Opinion statement Hepatocellular carcinoma is the fourth leading cause of cancer-related
deaths worldwide and its associated mortality rate is expected to rise within the next decade …

The gastrointestinal microbiome is a complex echosystem that establishes a symbiotic,
mutually beneficial relation with the host, being rather stable in health, but affected by age …

This review discusses the inconsistent recommendations on alcohol consumption and its
association with chronic disease, highlighting the need for an evidence-based consensus …

Since its discovery twenty-five years ago, the fat-derived hormone leptin has provided a
revolutionary framework for studying the physiological role of adipose tissue as an …

Jaundice in adults can be an indicator of significant underlying disease. It is caused by
elevated serum bilirubin levels in the unconjugated or conjugated form. The evaluation of …