Sequencing of nucleic acids with nanopores has emerged as a powerful tool offering rapid
readout, high accuracy, low cost and portability. This label-free method for sequencing at the …

Silicon photonics has developed into a mainstream technology driven by advances in
optical communications. The current generation has led to a proliferation of integrated …

Mammalian cells have about 30,000 times as many protein molecules as mRNA molecules,
which has major implications in the development of proteomics technologies. We discuss …

Mass spectrometry is unmatched in its versatility for studying practically any aspect of the
proteome. Because the foundations of mass spectrometry-based proteomics are complex …

Precise identification and quantification of amino acids is crucial for many biological
applications. Here we report a copper (II)-functionalized Mycobacterium smegmatis porin A …

Proteomics sets up single-cell and single-molecule solutions | Nature Methods Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Silicon photonics has developed into a mainstream technology driven by advances in
optical communications. The current generation has led to a proliferation of integrated …

Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Direct protein sequencing technologies with improved sensitivity and throughput are still
needed. Here, we propose an alternative method for peptide sequencing based on …

This paper reviews methods for detecting proteins based on molecular digitization, ie, the
isolation and detection of single protein molecules or singulated ensembles of protein …