[HTML][HTML] Alternative splicing in the mammalian nervous system: recent insights into mechanisms and functional roles

B Raj, BJ Blencowe - Neuron, 2015 - cell.com
High-throughput transcriptomic profiling approaches have revealed that alternative splicing
(AS) of precursor mRNAs, a fundamental process by which cells expand their transcriptomic …

MEF2: a central regulator of diverse developmental programs

MJ Potthoff, EN Olson - 2007 - journals.biologists.com
The myocyte enhancer factor 2 (MEF2) transcription factor acts as a lynchpin in the
transcriptional circuits that control cell differentiation and organogenesis. The spectrum of …

Direct observation of the rotation of F1-ATPase

H Noji, R Yasuda, M Yoshida, K Kinosita Jr - Nature, 1997 - nature.com
Cells employ a variety of linear motors, such as myosin1–3, kinesin4 and RNA polymerase5,
which move along and exert force on a filamentous structure. But only one rotary motor has …

Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

BL Black, EN Olson - Annual review of cell and developmental …, 1998 - annualreviews.org
▪ Abstract Metazoans contain multiple types of muscle cells that share several common
properties, including contractility, excitability, and expression of overlapping sets of muscle …

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C

Q Lin, J Schwarz, C Bucana, E N. Olson - Science, 1997 - science.org
Members of the myocyte enhancer factor–2 (MEF2) family of MADS (MCM1, agamous,
deficiens, serum response factor)–box transcription factors bind an AT–rich DNA sequence …

The MADS‐box family of transcription factors

P Shore, AD Sharrocks - European journal of biochemistry, 1995 - Wiley Online Library
The MADS‐box family of transcription factors has been defined on the basis of primary
sequence similarity amongst numerous proteins from a diverse range of eukaryotic …

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

JD Molkentin, BL Black, JF Martin, EN Olson - Cell, 1995 - cell.com
Members of the myocyte enhancer factor-2 (MEFS) family of MADS domain transcription
factors cannot induce myogenesis in transfected fibroblasts, but when coexpressed with the …

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis

DG Edmondson, GE Lyons, JF Martin… - …, 1994 - journals.biologists.com
Members of the MEF2 family of transcription factors bind a conserved A/T-rich sequence in
the control regions of many skeletal and cardiac muscle genes. To begin to assess the roles …

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

J Han, Y Jiang, Z Li, VV Kravchenko, RJ Ulevitch - Nature, 1997 - nature.com
For cells of the innate immune system to mount a host defence response to infection, they
must recognize products of microbial pathogens such as lipopolysaccharide (LPS), the …

[HTML][HTML] BMK1/ERK5 regulates serum‐induced early gene expression through transcription factor MEF2C

Y Kato, VV Kravchenko, RI Tapping, J Han… - The EMBO …, 1997 - embopress.org
Abstract Big MAP kinase 1 (BMK1), also known as ERK5, is a mitogen‐activated protein
(MAP) kinase member whose biological role is largely undefined. We have shown …