[HTML][HTML] Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies

A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

[HTML][HTML] Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 …

L Luo, M Liu, Y Fan, J Zhang, L Liu, Y Li… - Journal of …, 2022 - Springer
Background Neuronal pyroptosis and neuroinflammation with excess microglial activation
are widely involved in the early pathological process of ischemic stroke. Repetitive …

Cerium oxide nanoparticles with antioxidative neurorestoration for ischemic stroke

X Li, Z Han, T Wang, C Ma, H Li, H Lei, Y Yang… - Biomaterials, 2022 - Elsevier
Oxidative stress and mitochondrial damage are the main mechanisms of ischemia-
reperfusion injury in ischemic stroke. Herein, cerium oxide nanoparticles with powerful free …

The predictive role of systemic inflammation response index (SIRI) in the prognosis of stroke patients

Y Zhang, Z Xing, K Zhou, S Jiang - Clinical interventions in aging, 2021 - Taylor & Francis
Purpose Stroke is a disease associated with high mortality. Many inflammatory indicators
such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte …

[HTML][HTML] The important role of zinc in neurological diseases

Z Li, Y Liu, R Wei, VW Yong, M Xue - Biomolecules, 2022 - mdpi.com
Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components

K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

[HTML][HTML] The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Dental pulp stem cell‐derived exosomes alleviate cerebral ischaemia‐reperfusion injury through suppressing inflammatory response

S Li, L Luo, Y He, R Li, Y Xiang, Z Xing, Y Li… - Cell …, 2021 - Wiley Online Library
Objectives The study aimed to determine whether dental pulp stem cell‐derived exosomes
(DPSC‐Exos) exert protective effects against cerebral ischaemia‐reperfusion (I/R) injury and …

The landscape of biomimetic nanovesicles in brain diseases

Q You, F Liang, G Wu, F Cao, J Liu, Z He… - Advanced …, 2024 - Wiley Online Library
Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …