A tutorial: Laserspray ionization and related laser‐based ionization methods for use in mass spectrometry

S Trimpin - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This Tutorial is to provide a summary of parameters useful for successful outcomes of
laserspray ionization (LSI) and related methods that employ a laser to ablate a matrix …

Novel ionization processes for use in mass spectrometry:'Squeezing'nonvolatile analyte ions from crystals and droplets

S Trimpin - Rapid Communications in Mass Spectrometry, 2019 - Wiley Online Library
Together with my group and collaborators, I have been fortunate to have had a key role in
the discovery of new ionization processes that we developed into new flexible, sensitive …

Fundamental studies of new ionization technologies and insights from IMS-MS

S Trimpin, ED Inutan, S Karki, EA Elia… - Journal of The …, 2019 - ACS Publications
Exceptional ion mobility spectrometry mass spectrometry (IMS-MS) developments by von
Helden, Jarrold, and Clemmer provided technology that gives a view of chemical/biological …

Instrumentation development, improvement, simplification, and miniaturization: The multifunctional plate source for use in mass spectrometry

S Trimpin, E Inutan, H Coffinberger… - … Journal of Mass …, 2023 - journals.sagepub.com
In remembrance of Prof. Dr Przybylski, we are presenting a vision towards his beloved mass
spectrometry (MS) and its far-reaching promises outside of the academic laboratory. Sub …

Lasers for matrix‐assisted laser desorption ionization

KK Murray - Journal of Mass Spectrometry, 2021 - Wiley Online Library
Matrix‐assisted laser desorption ionization (MALDI) was introduced 35 years ago and has
advanced from a general method for producing intact ions from large biomolecules to wide …

Sublimation driven ionization for use in mass spectrometry: mechanistic implications

CN McEwen, ED Inutan… - Journal of the …, 2020 - ACS Publications
Sublimation has been known at least since the middle ages. This process is frequently
taught in schools through the use of phase diagrams. Astonishingly, such a well-known …

Toward understanding the ionization mechanism of matrix‐assisted ionization using mass spectrometry experiment and theory

C Lee, ED Inutan, JL Chen, MM Mukeku… - Rapid …, 2021 - Wiley Online Library
Rationale Matrix‐assisted ionization (MAI) mass spectrometry does not require voltages, a
laser beam, or added heat to initiate ionization, but it is strongly dependent on the choice of …

[HTML][HTML] Collision-induced dissociation of doubly-charged barium-cationized lipids generated from liquid samples by atmospheric pressure matrix-assisted laser …

OJ Hale, R Cramer - Analytical and bioanalytical chemistry, 2018 - Springer
Obtaining structural information for lipids such as phosphatidylcholines, in particular the
location of double bonds in their fatty acid constituents, is an ongoing challenge for mass …

An overview of biological applications and fundamentals of new inlet and vacuum ionization technologies

S Trimpin, DD Marshall, S Karki… - Rapid …, 2021 - Wiley Online Library
Rationale The developments of new ionization technologies based on processes previously
unknown to mass spectrometry (MS) have gained significant momentum. Herein we address …

Generation of multiply charged ions from homogeneous MALDI microcrystals

AA Patil, TKL Lại, CW Wang, GF Chen, BX Du… - International Journal of …, 2021 - Elsevier
The homogeneity of matrix assisted laser desorption/ionization (MALDI) microcrystals, laser
fluence, and the proton affinity (PA) of matrices determine the generation of multiply charged …