Metabolism reprogramming is critical for both cancer progression and effective immune
responses in the tumor microenvironment. Amino acid metabolism in different cells and their …

A wide spectrum of metabolites (mainly, the three major nutrients and their derivatives) can
be sensed by specific sensors, then trigger a series of signal transduction pathways and …

Extranodal natural killer (NK)/T-cell lymphoma is an aggressive malignancy of putative NK-
cell origin, with a minority deriving from the T-cell lineage. Pathologically, the malignancy …

Background The clinical outcome of extranodal natural killer T-cell lymphoma (ENKTL) has
improved substantially as a result of new treatment strategies with non-anthracycline-based …

Natural killer/T-cell lymphoma (NKTL) is a sub-type of Epstein–Barr virus (EBV)-related non-
Hodgkin lymphomas common in Asia and Latin America but rare elsewhere. Its …

Background Natural killer/T-cell lymphoma (NKTCL) is an Epstein–Barr virus (EBV)-
associated, highly aggressive lymphoma. Treatment outcome remains sub-optimal …

Extranodal natural killer/T-cell lymphoma, nasal type (ENKL) is a subtype of mature T-and
natural killer cell lymphomas characterized by its association with Epstein-Barr virus and …

Purpose To explore a more effective treatment for newly diagnosed stage IV, relapsed, or
refractory extranodal natural killer/T-cell lymphoma, nasal type (ENKL), we conducted a …

This study aimed to assess the efficacy and safety of treatment with avelumab, an anti–
programmed death ligand 1 (PD-L1) antibody, in patients with relapsed or refractory …

Despite much progress in the diagnosis and treatment of cancer, tumour diseases constitute
one of the main reasons of deaths worldwide. The side effects of chemotherapy and drug …