Inflammatory biomarkers on an LPS-induced RAW 264.7 cell model: A systematic review and meta-analysis

BM Facchin, GO Dos Reis, GN Vieira, ETB Mohr… - Inflammation …, 2022 - Springer
Introduction Several experimental models have been designed to promote the development
of new anti-inflammatory drugs. The in vitro model using RAW 264.7 cells has been widely …

Curcumin combination chemotherapy: The implication and efficacy in cancer

BL Tan, ME Norhaizan - Molecules, 2019 - mdpi.com
Many chemotherapeutic drugs have been used for the treatment of cancer, for instance,
doxorubicin, irinotecan, 5-fluorouracil, cisplatin, and paclitaxel. However, the effectiveness of …

Aspirin inhibits LPS-induced macrophage activation via the NF-κB pathway

Y Liu, S Fang, X Li, J Feng, J Du, L Guo, Y Su, J Zhou… - Scientific reports, 2017 - nature.com
Aspirin (acetylsalicylic acid, ASA) has been shown to improve bone marrow mesenchymal
stem cell-based calvarial bone regeneration by promoting osteogenesis and inhibiting …

The traditional use, structure, and immunostimulatory activity of bioactive polysaccharides from traditional Chinese root medicines: A review

S Bo, M Zhang, M Dan - Heliyon, 2024 - cell.com
As research on traditional Chinese medicine (TCM) has expanded, our understanding of the
role it can have in controlling the immune system has increased. Polysaccharides from …

Anti-inflammatory activity of the water extract of Chloranthus serratus roots in LPS-stimulated RAW264. 7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling …

S Sun, J Zhang, H Li, Y Du, S Li, A Li, X Suo… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Chloranthus serratus is a traditional Chinese medicine for
treating arthritis and bruises. Aim of the study To investigate the dose-effect relationship and …

Comparison of RAW264. 7, human whole blood and PBMC assays to screen for immunomodulators

I Elisia, HB Pae, V Lam, R Cederberg, E Hofs… - Journal of …, 2018 - Elsevier
The RAW264. 7 mouse macrophage cell line is used extensively to carry out in vitro screens
for immunomodulators. Compounds that are effective at reducing the expression of pro …

Novel isoquinoline alkaloid Litcubanine Aa potential anti-inflammatory candidate

H Xia, Y Liu, G Xia, Y Liu, S Lin, L Guo - Frontiers in Immunology, 2021 - frontiersin.org
Macrophages play a critical role in innate and adaptive immunity, and the regulation of
macrophage function in inflammatory disease treatment has been widely studied. Litsea …

Anti-inflammation of hydrogenated isoflavones in LPS-stimulated RAW264. 7 cells via inhibition of NF-κB and MAPK signaling pathways

K Li, W Hu, Y Yang, H Wen, W Li, B Wang - Molecular immunology, 2023 - Elsevier
Isoflavones are commonly found in diets, such as soybean and clover. Their anti-
inflammatory effects are due to the inhibition of the transcriptional regulation of NF-κB …

Tetramethylpyrazine attenuates lipopolysaccharide-induced cardiomyocyte injury via improving mitochondrial function mediated by 14-3-3γ

B Huang, J You, Y Qiao, Z Wu, D Liu, D Yin… - European Journal of …, 2018 - Elsevier
Lipopolysaccharide (LPS) is one of the many reasons that can cause myocardial injury. Our
previous works have demonstrated that 14-3-3γ could protect myocardium against LPS …

Anti‐Inflammatory Effect of a Polyphenol‐Enriched Fraction from Acalypha wilkesiana on Lipopolysaccharide‐Stimulated RAW 264.7 Macrophages and …

H Wu, H Pang, Y Chen, L Huang, H Liu… - Oxidative Medicine …, 2018 - Wiley Online Library
A polyphenol‐enriched fraction (PEF) from Acalypha wilkesiana, whose leaves have been
traditionally utilized for the treatment of diverse medical ailments, was investigated for the …