Dissection of pro-tumoral macrophage subtypes and immunosuppressive cells participating in M2 polarization

O Sezginer, N Unver - Inflammation Research, 2024 - Springer
Alternatively activated macrophage (M2) polarization can result in one of four subtypes
based on cytokines and signaling pathways associated with macrophage activation: M2a …

The role of regulatory T cells in cancer treatment resistance

A Dąbrowska, M Grubba, A Balihodzic, O Szot… - International Journal of …, 2023 - mdpi.com
Despite tremendous progress in cancer treatment in recent years, treatment resistance is still
a major challenge for a great number of patients. One of the main causes is regulatory T …

Phellinus linteus activates Treg cells via FAK to promote M2 macrophage polarization in hepatocellular carcinoma

F Chen, M Gong, D Weng, Z Jin, G Han, Z Yang… - Cancer Immunology …, 2024 - Springer
Hepatocellular carcinoma (HCC) is the most prevalent malignant tumor worldwide. Within
HCC's tumor microenvironment, focal adhesion kinase (FAK) plays a critical role. Regulatory …

Mismatch repair gene MSH6 correlates with the prognosis, immune status and immune checkpoint inhibitors response of endometrial cancer

LZ Zhou, HQ Xiao, J Chen - Frontiers in Immunology, 2024 - frontiersin.org
Objective Many patients treated with immune checkpoint inhibitors (ICIs) developed primary
or secondary drug resistance for unknown reasons. This study investigates whether …

Engineered biological nanoparticles as nanotherapeutics for tumor immunomodulation

JN Rahmat, J Liu, T Chen, ZH Li, Y Zhang - Chemical Society Reviews, 2024 - pubs.rsc.org
Biological nanoparticles, or bionanoparticles, are small molecules manufactured in living
systems with complex production and assembly machinery. The products of the assembly …

Extracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin‐9 dependent mechanism

A Lefebvre, C Trioën, S Renaud… - Journal of …, 2023 - Wiley Online Library
Nasopharyngeal carcinoma‐derived small extracellular vesicles (NPCSEVs) have an
immunosuppressive impact on the tumour microenvironment. In this study, we investigated …

Immune Evasion in Cancer Is Regulated by Tumor-Asociated Macrophages (TAMs): Targeting TAMs

M Jung, B Bonavida - Critical Reviews™ in Oncogenesis, 2024 - dl.begellhouse.com
Recent advancements in cancer treatment have explored a variety of approaches to address
the needs of patients. Recently, immunotherapy has evolved as an efficacious treatment for …

[HTML][HTML] M2 Macrophage Prominently Distributed in the Rat's Colon of DMH-Induced Inflammation Associated Colorectal Cancer

WA Omadhika, S Solikhah, AA Adrianto… - Asian Pacific Journal …, 2024 - ncbi.nlm.nih.gov
Objective: The aim of this study is to examine the M1 and M2 macrophages distribution in
the rat's colon of DMH-induced inflammation associated colorectal cancer. Methods: Colon …

EBV 及PD⁃ L1 在局部晚期鼻咽癌中的研究进展

罗丽华, 张思佳, 向东华, 易俊林 - 中国癌症防治杂志, 2022 - zgazfz.com
鼻咽癌是一种起源于鼻咽黏膜且与EB 病毒(epstein-barr virus, EBV) 感染有关的上皮性恶性
肿瘤. 血浆EBV DNA 拷贝数在鼻咽癌分期, 治疗, 预后及随访监测中均有重要价值 …

[PDF][PDF] Untersuchungen zur prognostischen und immunologischen Bedeutung der COX-2-und PPARgamma-Expression im Tumorgewebe bei Patientinnen mit …

NA Ansorge - 2023 - edoc.ub.uni-muenchen.de
Etwa 90% aller Vulvakarzinome sind Plattenepithelkarzinome [7]. Vereinfacht lässt sich das
Vulvakarzinom in zwei ätiologische Klassen einteilen. Zum einen wird bei Vulvakarzinomen …