Nonspecific binding—fundamental concepts and consequences for biosensing applications

A Frutiger, A Tanno, S Hwu, RF Tiefenauer… - Chemical …, 2021 - ACS Publications
Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Observation of liquid–liquid-phase separation and vesicle spreading during supported bilayer formation via liquid-phase transmission electron microscopy

A Rizvi, JT Mulvey, JP Patterson - Nano Letters, 2021 - ACS Publications
Liquid-phase transmission electron microscopy (LP-TEM) enables the real-time visualization
of nanoscale dynamics in solution. This technique has been used to study the formation and …

Lipid bilayer thickness measured by quantitative DIC reveals phase transitions and effects of substrate hydrophilicity

D Regan, J Williams, P Borri, W Langbein - Langmuir, 2019 - ACS Publications
Quantitative differential interference contrast microscopy is demonstrated here as a label-
free method, which is able to image and measure the thickness of lipid bilayers with 0.1 nm …

Electrochemiluminescent Ion-Channeling Framework for Membrane Binding and Transmembrane Activity Assays

J Chen, Y Zhao, Y Wan, L Zhu, B Li, J Wu, L Li… - Analytical …, 2022 - ACS Publications
Recent upgrades in the electrochemiluminescence (ECL) technique showcased its brilliant
knack in probing microscopic biointerfacial events, many of which were actually underlain by …

Wafer-scale bioactive substrate patterning by chemical lift-off lithography

CY Chen, CM Wang, HH Li, HH Chan… - Beilstein Journal of …, 2018 - beilstein-journals.org
The creation of bioactive substrates requires an appropriate interface molecular
environment control and adequate biological species recognition with minimum nonspecific …

Metal‐Supported Phospholipid Bilayers Formed by Redox Command

O Hmam, A Badia - Advanced Materials Interfaces, 2022 - Wiley Online Library
A surface‐confined redox reaction triggers the formation of single bilayer membranes from
small unilamellar vesicles of anionic or zwitterionic phospholipids onto gold surfaces …