Autoimmune diseases are chronic immune diseases characterized by dysregulation of
immune system, which ultimately results in a disruption in self-antigen tolerance. Cumulative …

Coeliac disease is a common small bowel enteropathy arising in genetically predisposed
individuals and caused by ingestion of gluten in the diet. Great advances have been made …

Ethnopharmacological relevance Poria cocos polysaccharides (PCP) are abundant in Poria
cocos (Schw.) Wolf (Poria). This is a common traditional Chinese medicine used to treat …

Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience
plasma membrane damage from a multitude of stressors in the extra-and intra-cellular …

Inflammasomes are key intracellular multimeric proteins able to initiate the cellular
inflammatory signaling pathway. NLRP3 inflammasome represents one of the main protein …

Celiac disease (CeD) is an autoimmune disorder induced by consuming gluten proteins
from wheat, barley, and rye. Glutens resist gastrointestinal proteolysis, resulting in peptides …

Celiac disease (CD) is an allergic intestinal disease caused primarily by gliadin and is
widespread in the population. Alpha gliadin peptide causes cellular damage by substantially …

Coeliac disease is a chronic and systemic autoimmune condition triggered by gluten
ingestion in genetically predisposed subjects. Currently, the only effective treatment …

Initially described as Th2 promoter cytokine, more recently, IL-33 has been recognized as an
alarmin, mainly in epithelial and endothelial cells. While localized in the nucleus acting as a …

Our aim was to understand mechanisms for clustering and cross-linking of gliadins, a wheat
seed storage protein type, monomeric in native state, but incorporated in network while …