Update on hypertrophic scar treatment

FB Rabello, CD Souza, JA Farina - Clinics, 2014 - SciELO Brasil
Scar formation is a consequence of the wound healing process that occurs when body
tissues are damaged by a physical injury. Hypertrophic scars and keloids are pathological …

Hypertrophic scars and keloids—a review of their pathophysiology, risk factors, and therapeutic management

D Wolfram, A Tzankov, P Pülzl… - Dermatologic …, 2009 - journals.lww.com
BACKGROUND Hypertrophic scars and keloids result from an abnormal fibrous wound
healing process in which tissue repair and regeneration-regulating mechanism control is …

[图书][B] Physical agents in rehabilitation-e book: from research to practice

MH Cameron - 2013 - books.google.com
NEW! Video clips on companion Evolve site demonstrate techniques and procedures
described in the text. NEW! Content specific to OTs has been added to the core text …

Evolution of silicone therapy and mechanism of action in scar management

TA Mustoe - Aesthetic plastic surgery, 2008 - Springer
Silicone-based products are widely used in the management of hypertrophic scarring and
keloids. This review discusses the range of products available and the clinical evidence of …

Nonsurgical management of hypertrophic scars: evidence-based therapies, standard practices, and emerging methods

BS Atiyeh - Aesthetic plastic surgery, 2007 - Springer
Hypertrophic scars, resulting from alterations in the normal processes of cutaneous wound
healing, are characterized by proliferation of dermal tissue with excessive deposition of …

Human matrix metalloproteinases: an ubiquitarian class of enzymes involved in several pathological processes

D Sbardella, GF Fasciglione, M Gioia, C Ciaccio… - Molecular aspects of …, 2012 - Elsevier
Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of
endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site …

Keloids and hypertrophic scars: a spectrum of clinical challenges

AP Trace, CW Enos, A Mantel, VM Harvey - American journal of clinical …, 2016 - Springer
Since their earliest description, keloids and hypertrophic scars have beleaguered patients
and clinicians alike. These scars can be aesthetically disfiguring, functionally debilitating …

Biomechanical regulation of cell orientation and fate

JI Lopez, JK Mouw, VM Weaver - Oncogene, 2008 - nature.com
Biomechanical regulation of tumor phenotypes have been noted for several decades, yet the
function of mechanics in the co-evolution of the tumor epithelium and altered cancer …

Compression therapy affects collagen type balance in hypertrophic scar

S Tejiram, J Zhang, TE Travis, BC Carney… - Journal of Surgical …, 2016 - Elsevier
Background The effects of pressure on hypertrophic scar are poorly understood. Decreased
extracellular matrix deposition is hypothesized to contribute to changes observed after …

A histological study on the effect of pressure therapy on the activities of myofibroblasts and keratinocytes in hypertrophic scar tissues after burn

CWP Li-Tsang, B Feng, L Huang, X Liu, B Shu… - Burns, 2015 - Elsevier
Although pressure therapy (PT) has been widely used as the first-line treatment for
hypertrophic scars (HS), the histopathological changes involved have seldom been studied …