Biologics for the use in chronic spontaneous urticaria: when and which

M Maurer, DA Khan, DEA Komi, AP Kaplan - The Journal of Allergy and …, 2021 - Elsevier
Guidelines for the treatment of chronic spontaneous urticaria (CSU) recommend the use of
the IgE-targeted biologic omalizumab in patients with antihistamine-refractory disease. The …

Chronic urticaria: advances in understanding of the disease and clinical management

L He, W Yi, X Huang, H Long, Q Lu - Clinical reviews in allergy & …, 2021 - Springer
Chronic urticaria (CU) is a common skin condition characterized by the recurrence of
wheals, with or without angioedema, which lasts for at least 6 weeks. Owing to its pruritus …

How to treat patients with chronic spontaneous urticaria with omalizumab: questions and answers

M Türk, L Carneiro-Leão, P Kolkhir, H Bonnekoh… - The Journal of Allergy …, 2020 - Elsevier
Omalizumab is an effective treatment for patients with chronic spontaneous urticaria (CSU).
In routine clinical practice, physicians often face complex cases of CSU and need to decide …

Stepping down treatment in chronic spontaneous urticaria: what we know and what we don't know

D Terhorst-Molawi, L Fox, F Siebenhaar, M Metz… - American Journal of …, 2023 - Springer
In chronic spontaneous urticaria (CSU), wheals, angioedema, or both appear spontaneously
for> 6 weeks. Current recommended treatment options for urticaria target mast cell …

Omalizumab in chronic spontaneous urticaria (CSU): real-life experience in dose/interval adjustments and treatment discontinuation

R Brás, C Costa, R Limão, LE Caldeira… - The Journal of Allergy …, 2023 - Elsevier
Background Data on real-life experience with omalizumab dose/interval adjustments are still
limited, as well as on omalizumab discontinuation. Objective To evaluate efficacy and safety …

Pediatric chronic spontaneous urticaria: a brief clinician's guide

M Votto, G Achilli, M De Filippo, A Licari… - Expert Review of …, 2022 - Taylor & Francis
Introduction Chronic urticaria (CU) appears with daily or intermittent/recurrent wheals
with/without angioedema for more than six weeks. When no specific eliciting factors are …

A global perspective on stepping down chronic spontaneous urticaria treatment: Results of the Urticaria Centers of Reference and Excellence SDown‐CSU study

M Türk, E Kocatürk, R Ertaş, LF Ensina… - Clinical and …, 2024 - Wiley Online Library
Background Although there have been significant advances in the treatment of chronic
spontaneous urticaria (CSU) in recent years, there remains a lack of clear guidance on …

Ligelizumab for the treatment of chronic spontaneous urticaria

B Wedi - Expert opinion on biological therapy, 2020 - Taylor & Francis
Introduction Due to daily hives with itch, sleeplessness, and unforeseen development of
angioedema, chronic spontaneous urticaria significantly impairs quality of life, often for …

Factors related to omalizumab drug survival and treatment responses in chronic urticaria

E Hasal, E Bulbul Baskan, S Yazici… - International archives of …, 2022 - karger.com
Introduction: This study aimed to evaluate factors affecting drug survival and treatment
response in patients with chronic urticaria treated with omalizumab in clinical practice …

Chronic spontaneous urticaria—status quo and future

S Melchers, JP Nicolay - Allergo Journal International, 2023 - Springer
Chronic spontaneous urticaria (CsU) is a chronic inflammatory dermatosis whose etiology is
not yet fully understood. In affected patients, it is often associated with a high limitation of …