The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …

This review assesses the abuse potential of medically-administered psilocybin, following the
structure of the 8 factors of the US Controlled Substances Act (CSA). Research suggests the …

Psilocybin and psilocin are controlled substances in many countries. These are the two main
hallucinogenic compounds of the “magic mushrooms” and both act as agonists or partial …

Psychedelic therapy: a roadmap for wider acceptance and utilization | Nature Medicine Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …

The need to identify effective therapies for the treatment of psychiatric disorders is a
particularly important issue in modern societies. In addition, difficulties in finding new drugs …

Depression is a major public health problem that affects approximately 4.4% of the global
population. Since conventional pharmacotherapies and psychotherapies are only partially …

After decades of prohibition, psychedelics are generating intense public and private interest.
Scientists are researching the therapeutic properties of these substances, and mounting …

Classical psychedelics are a group of drugs characterized by their activation of the serotonin-
2A (5-hydroxytryptamine-2A; 5-HT2A) receptor and the unique hallucinogenic and mystical …

Classic psychedelics refer to substances such as lysergic acid diethylamide (LSD),
psilocybin, ayahuasca, and mescaline, which induce altered states of consciousness by …

Patients who suffer from alcohol use disorders (AUDs) usually go through various socio-
behavioral and pathophysiological changes that take place in the brain and other organs …