Understanding the mechanisms of viral and bacterial coinfections in bovine respiratory disease: a comprehensive literature review of experimental evidence

M Gaudino, B Nagamine, MF Ducatez, G Meyer - Veterinary research, 2022 - Springer
Bovine respiratory disease (BRD) is one of the most important diseases impacting the global
cattle industry, resulting in significant economic loss. Commonly referred to as shipping …

[PDF][PDF] The immunology of bovine respiratory disease: recent advancements

JL McGill, RE Sacco - Veterinary Clinics of North America: Food Animal …, 2020 - Elsevier
The innate and adaptive immune systems are well equipped to protect the lung from
pathogen invasion. BRD is a complex syndrome, however, caused by multiple factors …

Regulatory T cells and T helper 17 cells in viral infection

Z Wan, Z Zhou, Y Liu, Y Lai, Y Luo… - Scandinavian Journal …, 2020 - Wiley Online Library
CD4+ T cells are the central element of the adaptive immune responses and protect the
body from a variety of pathogens. Starting from naive cells, CD4+ T cells can differentiate …

Efficacy of mucosal polyanhydride nanovaccine against respiratory syncytial virus infection in the neonatal calf

JL McGill, SM Kelly, P Kumar, S Speckhart… - Scientific Reports, 2018 - nature.com
Human respiratory syncytial virus (HRSV) is a leading cause of severe acute lower
respiratory tract infection in infants and children worldwide. Bovine RSV (BRSV) is closely …

Supplementing a Saccharomyces cerevisiae fermentation product modulates innate immune function and ameliorates bovine respiratory syncytial virus infection in …

AHA Mahmoud, JR Slate, S Hong, I Yoon… - Journal of Animal …, 2020 - academic.oup.com
The objectives of this study were to determine the effects of oral supplementation with
Saccharomyces cerevisiae fermentation products (SCFP; SmartCare and NutriTek; Diamond …

Special features of γδ T cells in ruminants

CL Baldwin, P Damani-Yokota, A Yirsaw, K Loonie… - Molecular …, 2021 - Elsevier
Ruminant γδ T cells were discovered in the mid-1980′ s shortly after a novel T cell receptor
(TCR) gene from murine cells was described in 1984 and the murine TCRγ gene locus in …

The bacterial and viral agents of BRDC: Immune evasion and vaccine developments

RL Bell, HL Turkington, SL Cosby - Vaccines, 2021 - mdpi.com
Bovine respiratory disease complex (BRDC) is a multifactorial disease of cattle which
presents as bacterial and viral pneumonia. The causative agents of BRDC work in synergy …

The trehalose glycolipid C18Brar promotes antibody and T-cell immune responses to Mannheimia haemolytica and Mycoplasma ovipneumoniae whole cell antigens …

SK Gupta, N Parlane, B Bridgeman, AT Lynch… - PLoS one, 2023 - journals.plos.org
Bronchopneumonia is a common respiratory disease in livestock. Mannheimia haemolytica
is considered the main causative pathogen leading to lung damage in sheep, with …

Aerosol vaccination with Bacille Calmette-Guerin induces a trained innate immune phenotype in calves

M Guerra-Maupome, DX Vang, JL McGill - PloS one, 2019 - journals.plos.org
Mycobacterium bovis Bacillus Calmette-Guérin (BCG) is a live attenuated vaccine for use
against tuberculosis (TB); however, it is known to reduce childhood mortality from infections …

Current animal models for understanding the pathology caused by the respiratory syncytial virus

MJ Altamirano-Lagos, FE Díaz, MA Mansilla… - Frontiers in …, 2019 - frontiersin.org
The human respiratory syncytial virus (hRSV) is the main etiologic agent of severe lower
respiratory tract infections that affect young children throughout the world, associated with …