The recent research progress of NF-κB signaling on the proliferation, migration, invasion, immune escape and drug resistance of glioblastoma
P Shi, J Xu, H Cui - International Journal of Molecular Sciences, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common and invasive primary central nervous
system tumor in humans, accounting for approximately 45–50% of all primary brain tumors …
system tumor in humans, accounting for approximately 45–50% of all primary brain tumors …
Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …
The platinum drug, cisplatin, is considered as among the most successful medications in
cancer treatment. However, due to its inherent toxicity and resistance limitations, research …
cancer treatment. However, due to its inherent toxicity and resistance limitations, research …
Modulation of the ubiquitin‐proteasome system by phytochemicals: Therapeutic implications in malignancies with an emphasis on brain tumors
Regarding the multimechanistic nature of cancers, current chemo‐or radiotherapies often
fail to eradicate disease pathology, and frequent relapses or resistance to therapies occur …
fail to eradicate disease pathology, and frequent relapses or resistance to therapies occur …
[HTML][HTML] Targeting oncogenic transcription factors in skin malignancies: An update on cancer stemness and therapeutic outcomes
The skin is the largest organ of the human body and prone to various diseases, including
cancer; thus, provides the first line of defense against exogenous biological and non …
cancer; thus, provides the first line of defense against exogenous biological and non …
Ubiquitin-proteasome system-based signature to predict the prognosis and drug sensitivity of hepatocellular carcinoma
J Zhang, L Liu, Z Wang, M Hou, Z Dong, J Yu… - Frontiers in …, 2023 - frontiersin.org
Background: Ubiquitin-proteasome system (UPS) is implicated in cancer occurrence and
progression. Targeting UPS is emerging as a promising therapeutic target for cancer …
progression. Targeting UPS is emerging as a promising therapeutic target for cancer …
[HTML][HTML] Unlocking the Mechanistic Potential of Thuja occidentalis for Managing Diabetic Neuropathy and Nephropathy
S Singh, TG Singh - Journal of Traditional and Complementary Medicine, 2024 - Elsevier
Diabetes mellitus and its debilitating microvascular complications, including diabetic
neuropathy and nephropathy, represent a growing global health burden. Despite advances …
neuropathy and nephropathy, represent a growing global health burden. Despite advances …
Correction: Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …
Correction for 'Addressing the gaps in homeostatic mechanisms of copper and copper
dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …
dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies
H Filali, OM El Yaagoubi, A Lahmadi, A Quessar… - Clinical Proteomics, 2022 - Springer
Background Regulatory degradation of intracellular proteins plays an essential role in most
biological processes, particularly in the control of cell proliferation and differentiation. In …
biological processes, particularly in the control of cell proliferation and differentiation. In …
Ubiquitin-specific peptidase 47 (USP47) regulates cutaneous oxidative injury through nicotinamide nucleotide transhydrogenase (NNT)
X Li, K Qian, Y Zhang, Y Zhang, Y Liu, C Sun… - Toxicology and Applied …, 2023 - Elsevier
Human skin is daily exposed to oxidative stresses in the environment such as physical
stimulation, chemical pollutants and pathogenic microorganisms, which are likely to cause …
stimulation, chemical pollutants and pathogenic microorganisms, which are likely to cause …
Inhibition of macrophage MAPK/NF-κB pathway and Th2 axis by mangiferin ameliorates MC903-induced atopic dermatitis
C Lu, SJ Deng, YJ Liu, SJ Yang, DM Qin… - International …, 2024 - Elsevier
Available online Atopic dermatitis (AD) is a chronic, persistent inflammatory skin disease
characterized by eczema-like lesions and itching. Although topical steroids have been …
characterized by eczema-like lesions and itching. Although topical steroids have been …