The recent research progress of NF-κB signaling on the proliferation, migration, invasion, immune escape and drug resistance of glioblastoma

P Shi, J Xu, H Cui - International Journal of Molecular Sciences, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common and invasive primary central nervous
system tumor in humans, accounting for approximately 45–50% of all primary brain tumors …

Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …

LW Njenga, SN Mbugua, RA Odhiambo… - Dalton Transactions, 2023 - pubs.rsc.org
The platinum drug, cisplatin, is considered as among the most successful medications in
cancer treatment. However, due to its inherent toxicity and resistance limitations, research …

Modulation of the ubiquitin‐proteasome system by phytochemicals: Therapeutic implications in malignancies with an emphasis on brain tumors

M Sanati, AR Afshari, SS Ahmadi, SA Moallem… - …, 2023 - Wiley Online Library
Regarding the multimechanistic nature of cancers, current chemo‐or radiotherapies often
fail to eradicate disease pathology, and frequent relapses or resistance to therapies occur …

[HTML][HTML] Targeting oncogenic transcription factors in skin malignancies: An update on cancer stemness and therapeutic outcomes

M Steinhoff, M Alam, A Ahmad, S Uddin… - Seminars in Cancer …, 2022 - Elsevier
The skin is the largest organ of the human body and prone to various diseases, including
cancer; thus, provides the first line of defense against exogenous biological and non …

Ubiquitin-proteasome system-based signature to predict the prognosis and drug sensitivity of hepatocellular carcinoma

J Zhang, L Liu, Z Wang, M Hou, Z Dong, J Yu… - Frontiers in …, 2023 - frontiersin.org
Background: Ubiquitin-proteasome system (UPS) is implicated in cancer occurrence and
progression. Targeting UPS is emerging as a promising therapeutic target for cancer …

[HTML][HTML] Unlocking the Mechanistic Potential of Thuja occidentalis for Managing Diabetic Neuropathy and Nephropathy

S Singh, TG Singh - Journal of Traditional and Complementary Medicine, 2024 - Elsevier
Diabetes mellitus and its debilitating microvascular complications, including diabetic
neuropathy and nephropathy, represent a growing global health burden. Despite advances …

Correction: Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …

LW Njenga, SN Mbugua, RA Odhiambo… - Dalton Transactions, 2024 - pubs.rsc.org
Correction for 'Addressing the gaps in homeostatic mechanisms of copper and copper
dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …

Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies

H Filali, OM El Yaagoubi, A Lahmadi, A Quessar… - Clinical Proteomics, 2022 - Springer
Background Regulatory degradation of intracellular proteins plays an essential role in most
biological processes, particularly in the control of cell proliferation and differentiation. In …

Ubiquitin-specific peptidase 47 (USP47) regulates cutaneous oxidative injury through nicotinamide nucleotide transhydrogenase (NNT)

X Li, K Qian, Y Zhang, Y Zhang, Y Liu, C Sun… - Toxicology and Applied …, 2023 - Elsevier
Human skin is daily exposed to oxidative stresses in the environment such as physical
stimulation, chemical pollutants and pathogenic microorganisms, which are likely to cause …

Inhibition of macrophage MAPK/NF-κB pathway and Th2 axis by mangiferin ameliorates MC903-induced atopic dermatitis

C Lu, SJ Deng, YJ Liu, SJ Yang, DM Qin… - International …, 2024 - Elsevier
Available online Atopic dermatitis (AD) is a chronic, persistent inflammatory skin disease
characterized by eczema-like lesions and itching. Although topical steroids have been …