Does regulation hold the key to optimizing lipopeptide production in Pseudomonas for biotechnology?

L Zhou, M Höfte, RC Hennessy - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Lipopeptides (LPs) produced by Pseudomonas spp. are specialized metabolites with
diverse structures and functions, including powerful biosurfactant and antimicrobial …

Polysaccharides and Peptides With Wound Healing Activity From Bacteria and Fungi

NP Arslan, T Orak, A Ozdemir, R Altun… - Journal of Basic …, 2024 - Wiley Online Library
Bacteria and fungi are natural sources of metabolites exhibiting diverse bioactive properties
such as wound healing, antioxidative, antibacterial, antifungal, anti‐inflammatory …

Computational Insights into Amide Bond Formation Catalyzed by the Condensation Domain of Nonribosomal Peptide Synthetases

B Mansour, JW Gauld - ACS Omega, 2024 - ACS Publications
Nonribosomal peptide synthetases (NRPSs) are important enzymes that synthesize an array
of nongenetically encoded peptides. The latter have diverse physicochemical properties and …

Breaking Cycles: Saponification‐Enhanced NMR Fingerprint Matching for the Identification and Stereochemical Evaluation of Cyclic Lipodepsipeptides from Natural …

P Muangkaew, D Prasad, V De Roo… - … A European Journal, 2024 - Wiley Online Library
We previously described NMR based fingerprint matching with peptide backbone
resonances as a fast and reliable structural dereplication approach for Pseudomonas cyclic …