Inflammation of the adipose tissues occurs in association with obesity. This inflammatory
process leads to the induction of cyclooxygenase-2 (COX-2) expression and a consequent …

Background: Currently, there is no clinical evidence of oncologic risk associated with fat
grafting, although its safety has been questioned. The authors investigated the risk of …

Obesity has been associated with an increased risk of postmenopausal breast cancer.
Adipokines and systemic inflammation have been hypothesized to underlie this association …

Background: Emerging published studies have indicated that adiponectin is involved in
tumorigenesis of breast cancer. However, the results of available studies were inconsistent …

Adipokines within the tumor microenvironment may play important roles in regulating the
early steps of breast cancer metastasis. Adiponectin (AdipoQ) is the most abundant …

Background: C-reactive protein (CRP) has been evaluated as a risk factor for breast cancer
in epidemiologic studies. However, results from prospective studies are inconsistent …

Background Colorectal cancer (CRC) is one of the most common cancers worldwide. The
tumor microenvironment is very important for determining cancer cell growth and spreading …

Molecular links between breast cancer risk factors and pro-oncogenic tissue alterations are
poorly understood. The goal of this study was to characterize the impact of overweight and …

Despite known age-related DNA methylation (aDNAm) changes in breast tumors, little is
known about aDNAm in normal breast tissues. Breast tissues from a cross-sectional study of …

Adipokines including leptin, adiponectin and resistin have been linked to risk of obesity-
related cancers potentially through low-grade chronic inflammation pathways. We aimed to …