Microneedles is the technique of drug delivery enhancement, which was primarily designed
for facilitating percutaneous drug delivery. Started from the development of simple solid …

Transdermal drug delivery offers several attractive advantages over the traditional oral and
parenteral routes. Particularly, in case of paediatric patients, it helps to overcome the issues …

Objectives Vesicular drug delivery has become a useful approach for therapeutic
administration of pharmaceutical compounds. Lipid vesicles have found application in …

Onychomycosis accounts for 50% of all nail disease cases and is commonly caused by
dermatophytes. It was primarily considered a cosmetic problem but has been garnering …

In this work, electro-responsive chitosan/ionic liquid-based hydrogels were synthetized for
the first time, envisaging the development of iontophoretic biomaterials for the controlled …

The treatment of onychomycosis remains problematic even though there are several potent
antifungal agents available for patient use. The aim of this investigation was to understand …

Abstract We hypothesised that Hansen Solubility Parameters (HSPs) can be used to predict
drug–nail affinities. Our aims were to:(i) determine the HSPs (δ D, δ P, δ H) of the nail plate …

NP213 (Novexatin®) is a novel antifungal peptide specifically designed for the topical
treatment of onychomycosis. NP213 was designed using host defense peptides (HDP) …

The fungal disease of the nail, onychomycosis, which is also the most prevalent nail
disturbance, demands effective topical treatment options considering the possible adverse …

Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs
through the thick multi-layered keratinized nail plate. The objective of this investigation was …