Synapses are intercellular junctions specialized for fast, point-to-point information transfer
from a presynaptic neuron to a postsynaptic cell. At a synapse, a presynaptic terminal …

Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlapping and interdigitated …

Social memory—the ability to recognize and remember familiar conspecifics—is critical for
the survival of an animal in its social group,. The dorsal CA2 (dCA2),–and ventral CA1 …

Synapse organizing proteins are multifaceted molecules that coordinate the complex
processes of brain development and plasticity at the level of individual synapses. Their …

AMPA-and NMDA-type glutamate receptors mediate distinct postsynaptic signals that differ
characteristically among synapses. How postsynaptic AMPA-and NMDA-receptor levels are …

Chemical synapses provide a vital foundation for neuron-neuron communication and overall
brain function. By tethering closely apposed molecular machinery for presynaptic …

The genetics underlying autism spectrum disorder (ASD) is complex and heterogeneous,
and de novo variants are found in genes converging in functional biological processes …

Aging drives a progressive decline in cognition and decreases synapse numbers and
synaptic function in the brain, thereby increasing the risk for neurodegenerative disease …

The subsynaptic organization of postsynaptic neurotransmitter receptors into nanoclusters
that are aligned with presynaptic release sites is essential for the high fidelity of synaptic …

Abstract Neuroligin-3 (Nlgn3) is an autism-associated cell-adhesion molecule that interacts
with neurexins and is robustly expressed in both neurons and astrocytes. Neuronal Nlgn3 is …